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Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors.
ACS Infect Dis. 2019 Mar 8;5(3):326-335. doi: 10.1021/acsinfecdis.8b00275. Epub 2019 Feb 4.
ACS Infect Dis. 2019.
PMID: 30682246
Backbone resonance assignment for the N-terminal region of bacterial tRNA-(N1G37) methyltransferase.
Li Y, Zhong W, Koay AZ, Ng HQ, Koh-Stenta X, Nah Q, Lim SH, Larsson A, Lescar J, Hill J, Dedon PC, Kang C.
Li Y, et al. Among authors: koh stenta x.
Biomol NMR Assign. 2019 Apr;13(1):49-53. doi: 10.1007/s12104-018-9849-9. Epub 2018 Oct 8.
Biomol NMR Assign. 2019.
PMID: 30298375
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Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K.
Huang C, et al. Among authors: koh stenta x.
ACS Med Chem Lett. 2019 May 23;10(6):978-984. doi: 10.1021/acsmedchemlett.9b00170. eCollection 2019 Jun 13.
ACS Med Chem Lett. 2019.
PMID: 31223458
Free PMC article.
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Identification of covalent active site inhibitors of dengue virus protease.
Koh-Stenta X, Joy J, Wang SF, Kwek PZ, Wee JL, Wan KF, Gayen S, Chen AS, Kang C, Lee MA, Poulsen A, Vasudevan SG, Hill J, Nacro K.
Koh-Stenta X, et al.
Drug Des Devel Ther. 2015 Dec 10;9:6389-99. doi: 10.2147/DDDT.S94207. eCollection 2015.
Drug Des Devel Ther. 2015.
PMID: 26677315
Free PMC article.
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Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques.
Koh-Stenta X, Joy J, Poulsen A, Li R, Tan Y, Shim Y, Min JH, Wu L, Ngo A, Peng J, Seetoh WG, Cao J, Wee JL, Kwek PZ, Hung A, Lakshmanan U, Flotow H, Guccione E, Hill J.
Koh-Stenta X, et al.
Biochem J. 2014 Jul 15;461(2):323-34. doi: 10.1042/BJ20140374.
Biochem J. 2014.
PMID: 24785241
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Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".
Huang C, Liew SS, Lin GR, Poulsen A, Ang MJY, Chia BCS, Chew SY, Kwek ZP, Wee JLK, Ong EH, Retna P, Baburajendran N, Li R, Yu W, Koh-Stenta X, Ngo A, Manesh S, Fulwood J, Ke Z, Chung HH, Sepramaniam S, Chew XH, Dinie N, Lee MA, Chew YS, Low CB, Pendharkar V, Manoharan V, Vuddagiri S, Sangthongpitag K, Joy J, Matter A, Hill J, Keller TH, Foo K.
Huang C, et al. Among authors: koh stenta x.
ACS Med Chem Lett. 2019 Jul 9;10(8):1240. doi: 10.1021/acsmedchemlett.9b00278. eCollection 2019 Aug 8.
ACS Med Chem Lett. 2019.
PMID: 31413812
Free PMC article.
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Discovery and characterisation of the automethylation properties of PRDM9.
Koh-Stenta X, Poulsen A, Li R, Wee JL, Kwek PZ, Chew SY, Peng J, Wu L, Guccione E, Joy J, Hill J.
Koh-Stenta X, et al.
Biochem J. 2017 Mar 7;474(6):971-982. doi: 10.1042/BCJ20161067.
Biochem J. 2017.
PMID: 28126738
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Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Liu BH, Jobichen C, Chia CSB, Chan THM, Tang JP, Chung TXY, Li J, Poulsen A, Hung AW, Koh-Stenta X, Tan YS, Verma CS, Tan HK, Wu CS, Li F, Hill J, Joy J, Yang H, Chai L, Sivaraman J, Tenen DG.
Liu BH, et al. Among authors: koh stenta x.
Proc Natl Acad Sci U S A. 2018 Jul 24;115(30):E7119-E7128. doi: 10.1073/pnas.1801253115. Epub 2018 Jul 5.
Proc Natl Acad Sci U S A. 2018.
PMID: 29976840
Free PMC article.
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