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Evolution-Guided Structural and Functional Analyses of the HERC Family Reveal an Ancient Marine Origin and Determinants of Antiviral Activity.
Paparisto E, Woods MW, Coleman MD, Moghadasi SA, Kochar DS, Tom SK, Kohio HP, Gibson RM, Rohringer TJ, Hunt NR, Di Gravio EJ, Zhang JY, Tian M, Gao Y, Arts EJ, Barr SD. Paparisto E, et al. Among authors: kohio hp. J Virol. 2018 Jun 13;92(13):e00528-18. doi: 10.1128/JVI.00528-18. Print 2018 Jul 1. J Virol. 2018. PMID: 29669830 Free PMC article.
Nitazoxanide and JIB-04 have broad-spectrum antiviral activity and inhibit SARS-CoV-2 replication in cell culture and coronavirus pathogenesis in a pig model.
Son J, Huang S, Zeng Q, Bricker TL, Case JB, Zhou J, Zang R, Liu Z, Chang X, Harastani HH, Chen L, Castro MFG, Zhao Y, Kohio HP, Hou G, Fan B, Niu B, Guo R, Rothlauf PW, Bailey AL, Wang X, Shi PY, Martinez ED, Whelan SPJ, Diamond MS, Boon ACM, Li B, Ding S. Son J, et al. Among authors: kohio hp. bioRxiv. 2020 Sep 25:2020.09.24.312165. doi: 10.1101/2020.09.24.312165. Preprint. bioRxiv. 2020. PMID: 32995798 Free PMC article.