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Structures of the extracellular domain of the type I tumor necrosis factor receptor.
Naismith JH, Devine TQ, Kohno T, Sprang SR. Naismith JH, et al. Among authors: kohno t. Structure. 1996 Nov 15;4(11):1251-62. doi: 10.1016/s0969-2126(96)00134-7. Structure. 1996. PMID: 8939750
Tumor necrosis factor (TNF)-alpha-induced interleukin-8 in human blood cultures discriminates neutralization by the p55 and p75 TNF soluble receptors.
Frishman JI, Edwards CK 3rd, Sonnenberg MG, Kohno T, Cohen AM, Dinarello CA. Frishman JI, et al. Among authors: kohno t. J Infect Dis. 2000 Dec;182(6):1722-30. doi: 10.1086/317605. Epub 2000 Nov 8. J Infect Dis. 2000. PMID: 11069245
Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo.
Van Zee KJ, Kohno T, Fischer E, Rock CS, Moldawer LL, Lowry SF. Van Zee KJ, et al. Among authors: kohno t. Proc Natl Acad Sci U S A. 1992 Jun 1;89(11):4845-9. doi: 10.1073/pnas.89.11.4845. Proc Natl Acad Sci U S A. 1992. PMID: 1317575 Free PMC article.
A second tumor necrosis factor receptor gene product can shed a naturally occurring tumor necrosis factor inhibitor.
Kohno T, Brewer MT, Baker SL, Schwartz PE, King MW, Hale KK, Squires CH, Thompson RC, Vannice JL. Kohno T, et al. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8331-5. doi: 10.1073/pnas.87.21.8331. Proc Natl Acad Sci U S A. 1990. PMID: 2172983 Free PMC article.
Determination of tumor necrosis factor binding protein disulfide structure: deviation of the fourth domain structure from the TNFR/NGFR family cysteine-rich region signature.
Jones MD, Hunt J, Liu JL, Patterson SD, Kohno T, Lu HS. Jones MD, et al. Among authors: kohno t. Biochemistry. 1997 Dec 2;36(48):14914-23. doi: 10.1021/bi971696k. Biochemistry. 1997. PMID: 9398215
Prevention of chronic relapsing experimental autoimmune encephalomyelitis by soluble tumor necrosis factor receptor I.
Selmaj K, Papierz W, Glabiński A, Kohno T. Selmaj K, et al. Among authors: kohno t. J Neuroimmunol. 1995 Feb;56(2):135-41. doi: 10.1016/0165-5728(94)00139-f. J Neuroimmunol. 1995. PMID: 7860709
Experimental autoimmune encephalomyelitis (EAE) was induced in SJL/J mice by adoptive transfer of T lymphocytes sensitized to myelin basic protein (MBP). sTNFrI completely blocked both clinical signs of disease and pathological changes that included CNS demyelination and i …
Experimental autoimmune encephalomyelitis (EAE) was induced in SJL/J mice by adoptive transfer of T lymphocytes sensitized to myelin …
Intratracheal administration of endotoxin and cytokines. IV. The soluble tumor necrosis factor receptor type I inhibits acute inflammation.
Ulich TR, Yin S, Remick DG, Russell D, Eisenberg SP, Kohno T. Ulich TR, et al. Among authors: kohno t. Am J Pathol. 1993 May;142(5):1335-8. Am J Pathol. 1993. PMID: 8388171 Free PMC article.
Combined inhibition of interleukin-1 and tumor necrosis factor in rodent endotoxemia: improved survival and organ function.
Russell DA, Tucker KK, Chinookoswong N, Thompson RC, Kohno T. Russell DA, et al. Among authors: kohno t. J Infect Dis. 1995 Jun;171(6):1528-38. doi: 10.1093/infdis/171.6.1528. J Infect Dis. 1995. PMID: 7769288
Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis.
Moreland LW, McCabe DP, Caldwell JR, Sack M, Weisman M, Henry G, Seely JE, Martin SW, Yee CL, Bendele AM, Frazier JL, Kohno T, Cosenza ME, Lyons SA, Dayer JM, Cohen AM, Edwards CK 3rd. Moreland LW, et al. Among authors: kohno t. J Rheumatol. 2000 Mar;27(3):601-9. J Rheumatol. 2000. PMID: 10743796 Clinical Trial.
Pharmacokinetics, immunogenicity, and efficacy of dimeric TNFR binding proteins in healthy and bacteremic baboon.
Solorzano CC, Kaibara A, Hess PJ, Edwards PD, Ksontini R, Abouhamze A, McDaniel S, Frazier J, Trujillo D, Kieft G, Seely J, Kohno T, Cosenza ME, Clare-Salzler M, MacKay SL, Martin SW, Moldawer LL, Edwards CK 3rd. Solorzano CC, et al. Among authors: kohno t. J Appl Physiol (1985). 1998 Apr;84(4):1119-30. doi: 10.1152/jappl.1998.84.4.1119. J Appl Physiol (1985). 1998. PMID: 9516174
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