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ACAT inhibitor pactimibe sulfate (CS-505) reduces and stabilizes atherosclerotic lesions by cholesterol-lowering and direct effects in apolipoprotein E-deficient mice.
Terasaka N, Miyazaki A, Kasanuki N, Ito K, Ubukata N, Koieyama T, Kitayama K, Tanimoto T, Maeda N, Inaba T. Terasaka N, et al. Among authors: koieyama t. Atherosclerosis. 2007 Feb;190(2):239-47. doi: 10.1016/j.atherosclerosis.2006.03.007. Epub 2006 Apr 19. Atherosclerosis. 2007. PMID: 16626720