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Click Chemistry: Diverse Chemical Function from a Few Good Reactions.
Kolb HC, Finn MG, Sharpless KB. Kolb HC, et al. Angew Chem Int Ed Engl. 2001 Jun 1;40(11):2004-2021. doi: 10.1002/1521-3773(20010601)40:11<2004::aid-anie2004>3.3.co;2-x. Angew Chem Int Ed Engl. 2001. PMID: 11433435
Integrated microfluidics for parallel screening of an in situ click chemistry library.
Wang J, Sui G, Mocharla VP, Lin RJ, Phelps ME, Kolb HC, Tseng HR. Wang J, et al. Angew Chem Int Ed Engl. 2006 Aug 11;45(32):5276-81. doi: 10.1002/anie.200601677. Angew Chem Int Ed Engl. 2006. PMID: 16927322 No abstract available.
Inhibitors of HIV-1 protease by using in situ click chemistry.
Whiting M, Muldoon J, Lin YC, Silverman SM, Lindstrom W, Olson AJ, Kolb HC, Finn MG, Sharpless KB, Elder JH, Fokin VV. Whiting M, et al. Angew Chem Int Ed Engl. 2006 Feb 20;45(9):1435-9. doi: 10.1002/anie.200502161. Angew Chem Int Ed Engl. 2006. PMID: 16425339 No abstract available.
"On water": unique reactivity of organic compounds in aqueous suspension.
Narayan S, Muldoon J, Finn MG, Fokin VV, Kolb HC, Sharpless KB. Narayan S, et al. Angew Chem Int Ed Engl. 2005 May 20;44(21):3275-9. doi: 10.1002/anie.200462883. Angew Chem Int Ed Engl. 2005. PMID: 15844112 No abstract available.
In situ click chemistry: enzyme-generated inhibitors of carbonic anhydrase II.
Mocharla VP, Colasson B, Lee LV, Röper S, Sharpless KB, Wong CH, Kolb HC. Mocharla VP, et al. Angew Chem Int Ed Engl. 2004 Dec 17;44(1):116-20. doi: 10.1002/anie.200461580. Angew Chem Int Ed Engl. 2004. PMID: 15599912 No abstract available.
The growing impact of click chemistry on drug discovery.
Kolb HC, Sharpless KB. Kolb HC, et al. Drug Discov Today. 2003 Dec 15;8(24):1128-37. doi: 10.1016/s1359-6446(03)02933-7. Drug Discov Today. 2003. PMID: 14678739 Review.
In situ click chemistry: enzyme inhibitors made to their own specifications.
Manetsch R, Krasiński A, Radić Z, Raushel J, Taylor P, Sharpless KB, Kolb HC. Manetsch R, et al. J Am Chem Soc. 2004 Oct 13;126(40):12809-18. doi: 10.1021/ja046382g. J Am Chem Soc. 2004. PMID: 15469276
Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of 18F-JNJ-64413739, a PET Radioligand for P2X7 Receptors.
Kolb HC, Barret O, Bhattacharya A, Chen G, Constantinescu C, Huang C, Letavic M, Tamagnan G, Xia CA, Zhang W, Szardenings AK. Kolb HC, et al. J Nucl Med. 2019 Aug;60(8):1154-1159. doi: 10.2967/jnumed.118.212696. Epub 2019 Feb 7. J Nucl Med. 2019. PMID: 30733317 Free article.
Synthesis, radiosynthesis, in vitro and first in vivo evaluation of a new matrix metalloproteinase inhibitor based on γ-fluorinated α-sulfonylaminohydroxamic acid.
Hugenberg V, Behrends M, Wagner S, Hermann S, Schäfers M, Kolb HC, Szardenings K, Walsh JC, Gomez LF, Kopka K, Haufe G. Hugenberg V, et al. Among authors: kolb hc. EJNMMI Radiopharm Chem. 2018 Jul 27;3:10. doi: 10.1186/s41181-018-0045-0. eCollection 2018 Dec. EJNMMI Radiopharm Chem. 2018. PMID: 30101186 Free PMC article.
S-[18F]THK-5117-PET and [11C]PIB-PET Imaging in Idiopathic Normal Pressure Hydrocephalus in Relation to Confirmed Amyloid-β Plaques and Tau in Brain Biopsies.
Leinonen V, Rauramaa T, Johansson J, Bottelbergs A, Tesseur I, van der Ark P, Pemberton D, Koivisto AM, Jääskeläinen JE, Hiltunen M, Herukka SK, Blennow K, Zetterberg H, Jokinen P, Rokka J, Helin S, Haaparanta-Solin M, Solin O, Okamura N, Kolb HC, Rinne JO. Leinonen V, et al. Among authors: kolb hc. J Alzheimers Dis. 2018;64(1):171-179. doi: 10.3233/JAD-180071. J Alzheimers Dis. 2018. PMID: 29865068
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