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When kinases meet mathematics: the systems biology of MAPK signalling.
Kolch W, Calder M, Gilbert D. Kolch W, et al. FEBS Lett. 2005 Mar 21;579(8):1891-5. doi: 10.1016/j.febslet.2005.02.002. FEBS Lett. 2005. PMID: 15763569 Review.
Cell-type specific integration of cross-talk between extracellular signal-regulated kinase and cAMP signaling.
Houslay MD, Kolch W. Houslay MD, et al. Among authors: kolch w. Mol Pharmacol. 2000 Oct;58(4):659-68. Mol Pharmacol. 2000. PMID: 10999934 Review. No abstract available.
Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions.
Kolch W. Kolch W. Biochem J. 2000 Oct 15;351 Pt 2(Pt 2):289-305. Biochem J. 2000. PMID: 11023813 Free PMC article. Review.
Regulation of Raf-1 activation and signalling by dephosphorylation.
Dhillon AS, Meikle S, Yazici Z, Eulitz M, Kolch W. Dhillon AS, et al. Among authors: kolch w. EMBO J. 2002 Jan 15;21(1-2):64-71. doi: 10.1093/emboj/21.1.64. EMBO J. 2002. PMID: 11782426 Free PMC article.
Extracellular signal regulated kinase (ERK)/mitogen activated protein kinase (MAPK)-independent functions of Raf kinases.
Hindley A, Kolch W. Hindley A, et al. Among authors: kolch w. J Cell Sci. 2002 Apr 15;115(Pt 8):1575-81. J Cell Sci. 2002. PMID: 11950876 Review.
Ras/Raf signalling and emerging pharmacotherapeutic targets.
Kolch W. Kolch W. Expert Opin Pharmacother. 2002 Jun;3(6):709-18. doi: 10.1517/14656566.3.6.709. Expert Opin Pharmacother. 2002. PMID: 12036410 Review.
Untying the regulation of the Raf-1 kinase.
Dhillon AS, Kolch W. Dhillon AS, et al. Among authors: kolch w. Arch Biochem Biophys. 2002 Aug 1;404(1):3-9. doi: 10.1016/s0003-9861(02)00244-8. Arch Biochem Biophys. 2002. PMID: 12127063 Review.
The role of MAPK pathways in the action of chemotherapeutic drugs.
Boldt S, Weidle UH, Kolch W. Boldt S, et al. Among authors: kolch w. Carcinogenesis. 2002 Nov;23(11):1831-8. doi: 10.1093/carcin/23.11.1831. Carcinogenesis. 2002. PMID: 12419831
The kinase domain of MEKK1 induces apoptosis by dysregulation of MAP kinase pathways.
Boldt S, Weidle UH, Kolch W. Boldt S, et al. Among authors: kolch w. Exp Cell Res. 2003 Feb 1;283(1):80-90. doi: 10.1016/s0014-4827(02)00018-6. Exp Cell Res. 2003. PMID: 12565821
A Raf-1 mutant that dissociates MEK/extracellular signal-regulated kinase activation from malignant transformation and differentiation but not proliferation.
Dhillon AS, Meikle S, Peyssonnaux C, Grindlay J, Kaiser C, Steen H, Shaw PE, Mischak H, Eychène A, Kolch W. Dhillon AS, et al. Among authors: kolch w. Mol Cell Biol. 2003 Mar;23(6):1983-93. doi: 10.1128/mcb.23.6.1983-1993.2003. Mol Cell Biol. 2003. PMID: 12612072 Free PMC article.
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