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268 results
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A hidden oncogenic positive feedback loop caused by crosstalk between Wnt and ERK pathways.
Kim D, Rath O, Kolch W, Cho KH. Kim D, et al. Among authors: kolch w. Oncogene. 2007 Jul 5;26(31):4571-9. doi: 10.1038/sj.onc.1210230. Epub 2007 Jan 22. Oncogene. 2007. PMID: 17237813
PKC epsilon functions as an oncogene by enhancing activation of the Raf kinase.
Cacace AM, Ueffing M, Philipp A, Han EK, Kolch W, Weinstein IB. Cacace AM, et al. Among authors: kolch w. Oncogene. 1996 Dec 19;13(12):2517-26. Oncogene. 1996. PMID: 9000126
Inhibition of Raf-1 signaling by a monoclonal antibody, which interferes with Raf-1 activation and with Mek substrate binding.
Kolch W, Philipp A, Mischak H, Dutil EM, Mullen TM, Feramisco JR, Meinkoth JL, Rose DW. Kolch W, et al. Oncogene. 1996 Sep 19;13(6):1305-14. Oncogene. 1996. PMID: 8808705
MAP kinase signalling pathways in cancer.
Dhillon AS, Hagan S, Rath O, Kolch W. Dhillon AS, et al. Among authors: kolch w. Oncogene. 2007 May 14;26(22):3279-90. doi: 10.1038/sj.onc.1210421. Oncogene. 2007. PMID: 17496922 Review.
Mapping of signaling pathways by functional interaction proteomics.
von Kriegsheim A, Preisinger C, Kolch W. von Kriegsheim A, et al. Among authors: kolch w. Methods Mol Biol. 2008;484:177-92. doi: 10.1007/978-1-59745-398-1_12. Methods Mol Biol. 2008. PMID: 18592180
A 19S proteasomal subunit cooperates with an ERK MAPK-regulated degron to regulate accumulation of Fra-1 in tumour cells.
Pakay JL, Diesch J, Gilan O, Yip YY, Sayan E, Kolch W, Mariadason JM, Hannan RD, Tulchinsky E, Dhillon AS. Pakay JL, et al. Among authors: kolch w. Oncogene. 2012 Apr 5;31(14):1817-24. doi: 10.1038/onc.2011.375. Epub 2011 Aug 29. Oncogene. 2012. PMID: 21874050
The RASSF8 candidate tumor suppressor inhibits cell growth and regulates the Wnt and NF-kappaB signaling pathways.
Lock FE, Underhill-Day N, Dunwell T, Matallanas D, Cooper W, Hesson L, Recino A, Ward A, Pavlova T, Zabarovsky E, Grant MM, Maher ER, Chalmers AD, Kolch W, Latif F. Lock FE, et al. Among authors: kolch w. Oncogene. 2010 Jul 29;29(30):4307-16. doi: 10.1038/onc.2010.192. Epub 2010 May 31. Oncogene. 2010. PMID: 20514026
Prolonged vs transient roles for early cell cycle signaling components.
Rose DW, Xiao S, Pillay TS, Kolch W, Olefsky JM. Rose DW, et al. Among authors: kolch w. Oncogene. 1998 Aug 20;17(7):889-99. doi: 10.1038/sj.onc.1201997. Oncogene. 1998. PMID: 9780005
The APC network regulates the removal of mutated cells from colonic crypts.
Song JH, Huels DJ, Ridgway RA, Sansom OJ, Kholodenko BN, Kolch W, Cho KH. Song JH, et al. Among authors: kolch w. Cell Rep. 2014 Apr 10;7(1):94-103. doi: 10.1016/j.celrep.2014.02.043. Epub 2014 Mar 27. Cell Rep. 2014. PMID: 24685131
Positive- and negative-feedback regulations coordinate the dynamic behavior of the Ras-Raf-MEK-ERK signal transduction pathway.
Shin SY, Rath O, Choo SM, Fee F, McFerran B, Kolch W, Cho KH. Shin SY, et al. Among authors: kolch w. J Cell Sci. 2009 Feb 1;122(Pt 3):425-35. doi: 10.1242/jcs.036319. J Cell Sci. 2009. PMID: 19158341
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