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The nuts and bolts of AGC protein kinases.
Pearce LR, Komander D, Alessi DR. Pearce LR, et al. Among authors: komander d. Nat Rev Mol Cell Biol. 2010 Jan;11(1):9-22. doi: 10.1038/nrm2822. Nat Rev Mol Cell Biol. 2010. PMID: 20027184 Review.
PDK1, the master regulator of AGC kinase signal transduction.
Mora A, Komander D, van Aalten DM, Alessi DR. Mora A, et al. Among authors: komander d. Semin Cell Dev Biol. 2004 Apr;15(2):161-70. doi: 10.1016/j.semcdb.2003.12.022. Semin Cell Dev Biol. 2004. PMID: 15209375 Review.
Analysis of the LKB1-STRAD-MO25 complex.
Boudeau J, Scott JW, Resta N, Deak M, Kieloch A, Komander D, Hardie DG, Prescott AR, van Aalten DM, Alessi DR. Boudeau J, et al. Among authors: komander d. J Cell Sci. 2004 Dec 15;117(Pt 26):6365-75. doi: 10.1242/jcs.01571. Epub 2004 Nov 23. J Cell Sci. 2004. PMID: 15561763
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistance.
Bayascas JR, Wullschleger S, Sakamoto K, García-Martínez JM, Clacher C, Komander D, van Aalten DM, Boini KM, Lang F, Lipina C, Logie L, Sutherland C, Chudek JA, van Diepen JA, Voshol PJ, Lucocq JM, Alessi DR. Bayascas JR, et al. Among authors: komander d. Mol Cell Biol. 2008 May;28(10):3258-72. doi: 10.1128/MCB.02032-07. Epub 2008 Mar 17. Mol Cell Biol. 2008. PMID: 18347057 Free PMC article.
130 results