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Autophagy regulates lipid metabolism.
Singh R, Kaushik S, Wang Y, Xiang Y, Novak I, Komatsu M, Tanaka K, Cuervo AM, Czaja MJ. Singh R, et al. Among authors: komatsu m. Nature. 2009 Apr 30;458(7242):1131-5. doi: 10.1038/nature07976. Epub 2009 Apr 1. Nature. 2009. PMID: 19339967 Free PMC article.
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production.
Saitoh T, Fujita N, Jang MH, Uematsu S, Yang BG, Satoh T, Omori H, Noda T, Yamamoto N, Komatsu M, Tanaka K, Kawai T, Tsujimura T, Takeuchi O, Yoshimori T, Akira S. Saitoh T, et al. Among authors: komatsu m. Nature. 2008 Nov 13;456(7219):264-8. doi: 10.1038/nature07383. Epub 2008 Oct 5. Nature. 2008. PMID: 18849965
Autophagy and neurodegeneration.
Komatsu M, Kominami E, Tanaka K. Komatsu M, et al. Autophagy. 2006 Oct-Dec;2(4):315-7. doi: 10.4161/auto.2974. Epub 2006 Oct 2. Autophagy. 2006. PMID: 16874063
Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes.
Klionsky DJ, Abeliovich H, Agostinis P, Agrawal DK, Aliev G, Askew DS, Baba M, Baehrecke EH, Bahr BA, Ballabio A, Bamber BA, Bassham DC, Bergamini E, Bi X, Biard-Piechaczyk M, Blum JS, Bredesen DE, Brodsky JL, Brumell JH, Brunk UT, Bursch W, Camougrand N, Cebollero E, Cecconi F, Chen Y, Chin LS, Choi A, Chu CT, Chung J, Clarke PG, Clark RS, Clarke SG, Clavé C, Cleveland JL, Codogno P, Colombo MI, Coto-Montes A, Cregg JM, Cuervo AM, Debnath J, Demarchi F, Dennis PB, Dennis PA, Deretic V, Devenish RJ, Di Sano F, Dice JF, Difiglia M, Dinesh-Kumar S, Distelhorst CW, Djavaheri-Mergny M, Dorsey FC, Dröge W, Dron M, Dunn WA Jr, Duszenko M, Eissa NT, Elazar Z, Esclatine A, Eskelinen EL, Fésüs L, Finley KD, Fuentes JM, Fueyo J, Fujisaki K, Galliot B, Gao FB, Gewirtz DA, Gibson SB, Gohla A, Goldberg AL, Gonzalez R, González-Estévez C, Gorski S, Gottlieb RA, Häussinger D, He YW, Heidenreich K, Hill JA, Høyer-Hansen M, Hu X, Huang WP, Iwasaki A, Jäättelä M, Jackson WT, Jiang X, Jin S, Johansen T, Jung JU, Kadowaki M, Kang C, Kelekar A, Kessel DH, Kiel JA, Kim HP, Kimchi A, Kinsella TJ, Kiselyov K, Kitamoto K, Knecht E, Komatsu M, Kominami E, Kondo S, Kovács AL, Kroemer G, Kuan CY, Kuma… See abstract for full author list ➔ Klionsky DJ, et al. Among authors: komatsu m. Autophagy. 2008 Feb;4(2):151-75. doi: 10.4161/auto.5338. Epub 2007 Nov 21. Autophagy. 2008. PMID: 18188003 Free PMC article. Review.
Selective turnover of p62/A170/SQSTM1 by autophagy.
Ichimura Y, Kominami E, Tanaka K, Komatsu M. Ichimura Y, et al. Among authors: komatsu m. Autophagy. 2008 Nov;4(8):1063-6. doi: 10.4161/auto.6826. Epub 2008 Nov 20. Autophagy. 2008. PMID: 18776737
LC3B is indispensable for selective autophagy of p62 but not basal autophagy.
Maruyama Y, Sou YS, Kageyama S, Takahashi T, Ueno T, Tanaka K, Komatsu M, Ichimura Y. Maruyama Y, et al. Among authors: komatsu m. Biochem Biophys Res Commun. 2014 Mar 28;446(1):309-15. doi: 10.1016/j.bbrc.2014.02.093. Epub 2014 Feb 28. Biochem Biophys Res Commun. 2014. PMID: 24582747
The selective autophagy substrate p62 activates the stress responsive transcription factor Nrf2 through inactivation of Keap1.
Komatsu M, Kurokawa H, Waguri S, Taguchi K, Kobayashi A, Ichimura Y, Sou YS, Ueno I, Sakamoto A, Tong KI, Kim M, Nishito Y, Iemura S, Natsume T, Ueno T, Kominami E, Motohashi H, Tanaka K, Yamamoto M. Komatsu M, et al. Nat Cell Biol. 2010 Mar;12(3):213-23. doi: 10.1038/ncb2021. Epub 2010 Feb 21. Nat Cell Biol. 2010. PMID: 20173742
1,725 results