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Suppression of autophagy in osteocytes mimics skeletal aging.
Onal M, Piemontese M, Xiong J, Wang Y, Han L, Ye S, Komatsu M, Selig M, Weinstein RS, Zhao H, Jilka RL, Almeida M, Manolagas SC, O'Brien CA. Onal M, et al. Among authors: komatsu m. J Biol Chem. 2013 Jun 14;288(24):17432-40. doi: 10.1074/jbc.M112.444190. Epub 2013 May 3. J Biol Chem. 2013. PMID: 23645674 Free PMC article.
Proteasome dysfunction activates autophagy and the Keap1-Nrf2 pathway.
Kageyama S, Sou YS, Uemura T, Kametaka S, Saito T, Ishimura R, Kouno T, Bedford L, Mayer RJ, Lee MS, Yamamoto M, Waguri S, Tanaka K, Komatsu M. Kageyama S, et al. Among authors: komatsu m. J Biol Chem. 2014 Sep 5;289(36):24944-55. doi: 10.1074/jbc.M114.580357. Epub 2014 Jul 21. J Biol Chem. 2014. PMID: 25049227 Free PMC article.
Excess peroxisomes are degraded by autophagic machinery in mammals.
Iwata J, Ezaki J, Komatsu M, Yokota S, Ueno T, Tanida I, Chiba T, Tanaka K, Kominami E. Iwata J, et al. Among authors: komatsu m. J Biol Chem. 2006 Feb 17;281(7):4035-41. doi: 10.1074/jbc.M512283200. Epub 2005 Dec 6. J Biol Chem. 2006. PMID: 16332691 Free article.
Structural basis for sorting mechanism of p62 in selective autophagy.
Ichimura Y, Kumanomidou T, Sou YS, Mizushima T, Ezaki J, Ueno T, Kominami E, Yamane T, Tanaka K, Komatsu M. Ichimura Y, et al. Among authors: komatsu m. J Biol Chem. 2008 Aug 15;283(33):22847-57. doi: 10.1074/jbc.M802182200. Epub 2008 Jun 4. J Biol Chem. 2008. PMID: 18524774 Free article.
The CCR4-NOT deadenylase complex controls Atg7-dependent cell death and heart function.
Yamaguchi T, Suzuki T, Sato T, Takahashi A, Watanabe H, Kadowaki A, Natsui M, Inagaki H, Arakawa S, Nakaoka S, Koizumi Y, Seki S, Adachi S, Fukao A, Fujiwara T, Natsume T, Kimura A, Komatsu M, Shimizu S, Ito H, Suzuki Y, Penninger JM, Yamamoto T, Imai Y, Kuba K. Yamaguchi T, et al. Among authors: komatsu m. Sci Signal. 2018 Feb 6;11(516):eaan3638. doi: 10.1126/scisignal.aan3638. Sci Signal. 2018. PMID: 29438013
1,725 results