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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1846 1
1875 1
1886 1
1887 1
1889 1
1890 1
1916 1
1926 2
1927 5
1928 2
1929 3
1930 4
1931 5
1932 3
1933 1
1934 2
1935 2
1943 1
1945 2
1946 1
1947 1
1949 1
1950 3
1951 3
1952 2
1953 4
1954 5
1955 4
1956 2
1957 1
1958 5
1959 3
1960 2
1961 7
1962 4
1963 20
1964 28
1965 20
1966 9
1967 14
1968 12
1969 22
1970 14
1971 20
1972 22
1973 19
1974 25
1975 73
1976 71
1977 72
1978 84
1979 90
1980 91
1981 77
1982 105
1983 119
1984 144
1985 143
1986 165
1987 241
1988 247
1989 313
1990 521
1991 398
1992 397
1993 425
1994 366
1995 380
1996 411
1997 398
1998 389
1999 408
2000 467
2001 554
2002 557
2003 586
2004 617
2005 728
2006 740
2007 753
2008 753
2009 905
2010 990
2011 1030
2012 1100
2013 1426
2014 1954
2015 2366
2016 2555
2017 2608
2018 2917
2019 3381
2020 4092
2021 4864
2022 5052
2023 5228
2024 5633
2025 6399
2026 4257

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62,286 results

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The following term was not found in PubMed: Komerally
Page 1
Compartmentation and functions of sphingolipids.
Körner C, Fröhlich F. Körner C, et al. Curr Opin Cell Biol. 2022 Feb;74:104-111. doi: 10.1016/j.ceb.2022.01.006. Epub 2022 Feb 25. Curr Opin Cell Biol. 2022. PMID: 35228099 Review.
SL biosynthesis is therefore highly compartmentalized. Maintaining SL levels is necessary for the function of multiple trafficking pathways. One major challenge is to decipher the complex regulatory networks controlling SL biosynthesis, the coordination of ve …
SL biosynthesis is therefore highly compartmentalized. Maintaining SL levels is necessary for the function of multiple traffic …
SLKB: synthetic lethality knowledge base.
Gökbağ B, Tang S, Fan K, Cheng L, Yu L, Zhao Y, Li L. Gökbağ B, et al. Nucleic Acids Res. 2024 Jan 5;52(D1):D1418-D1428. doi: 10.1093/nar/gkad806. Nucleic Acids Res. 2024. PMID: 37889037 Free PMC article.
The SL network generated from all data in SLKB shows a greater likelihood of SL gene pair connectivity with other SL gene pairs than non-SL pairs. Comparison of SL networks between two cell lines demonstrated greater likelihood to share SL …
The SL network generated from all data in SLKB shows a greater likelihood of SL gene pair connectivity with other SL ge …
Paralog-based synthetic lethality: rationales and applications.
Xin Y, Zhang Y. Xin Y, et al. Front Oncol. 2023 Jun 7;13:1168143. doi: 10.3389/fonc.2023.1168143. eCollection 2023. Front Oncol. 2023. PMID: 37350942 Free PMC article. Review.
Tumor cells can result from gene mutations and over-expression. Synthetic lethality (SL) offers a desirable setting where cancer cells bearing one mutated gene of an SL gene pair can be specifically targeted by disrupting the function of the other genes, while leavi …
Tumor cells can result from gene mutations and over-expression. Synthetic lethality (SL) offers a desirable setting where cancer cell …
SL trans-splicing: easy come or easy go?
Hastings KE. Hastings KE. Trends Genet. 2005 Apr;21(4):240-7. doi: 10.1016/j.tig.2005.02.005. Trends Genet. 2005. PMID: 15797620 Review.
Recent studies have discovered SL trans-splicing in new metazoan phyla, including the chordates. Its discovery in chordates identifies, for the first time, a phylum that clearly contains both trans-splicing and non-trans-splicing major groups, and defines a limited and wel …
Recent studies have discovered SL trans-splicing in new metazoan phyla, including the chordates. Its discovery in chordates identifie …
SL-scan identifies synthetic lethal interactions in cancer using metabolic networks.
Zangene E, Marashi SA, Montazeri H. Zangene E, et al. Sci Rep. 2023 Sep 22;13(1):15763. doi: 10.1038/s41598-023-42992-4. Sci Rep. 2023. PMID: 37737478 Free PMC article.
In this study, we developed the SL-scan pipeline based on metabolic network modeling to discover SL interaction. The SL-scan pipeline identifies the association between simulated Flux Balance Analysis knockout scores and mutation data across cancer cell lines …
In this study, we developed the SL-scan pipeline based on metabolic network modeling to discover SL interaction. The SL …
Perception and Signaling of Strigolactones.
Marzec M. Marzec M. Front Plant Sci. 2016 Aug 23;7:1260. doi: 10.3389/fpls.2016.01260. eCollection 2016. Front Plant Sci. 2016. PMID: 27602041 Free PMC article. Review.
However, some of SL signaling features seem to be specific for the SL signaling pathway. These include the enzymatic activity of the SL receptor and its destabilization caused by SLs. This review summarizes the current knowledge about SL signaling path …
However, some of SL signaling features seem to be specific for the SL signaling pathway. These include the enzymatic activity …
SL(2)MF: Predicting Synthetic Lethality in Human Cancers via Logistic Matrix Factorization.
Liu Y, Wu M, Liu C, Li XL, Zheng J. Liu Y, et al. IEEE/ACM Trans Comput Biol Bioinform. 2020 May-Jun;17(3):748-757. doi: 10.1109/TCBB.2019.2909908. Epub 2019 Apr 9. IEEE/ACM Trans Comput Biol Bioinform. 2020. PMID: 30969932
Therefore, computational prediction methods are needed to address these issues. This paper proposes a novel SL prediction method, named SL(2) MF, which employs logistic matrix factorization to learn latent representations of genes from the observed SL data. T …
Therefore, computational prediction methods are needed to address these issues. This paper proposes a novel SL prediction method, nam …
Computational methods, databases and tools for synthetic lethality prediction.
Wang J, Zhang Q, Han J, Zhao Y, Zhao C, Yan B, Dai C, Wu L, Wen Y, Zhang Y, Leng D, Wang Z, Yang X, He S, Bo X. Wang J, et al. Brief Bioinform. 2022 May 13;23(3):bbac106. doi: 10.1093/bib/bbac106. Brief Bioinform. 2022. PMID: 35352098 Free PMC article. Review.
The key point to exploiting SL-based cancer therapy is the identification of robust SL pairs. Although many wet-lab-based methods have been developed to screen SL pairs, known SL pairs are less than 0.1% of all potential pairs due to large number of hu …
The key point to exploiting SL-based cancer therapy is the identification of robust SL pairs. Although many wet-lab-based meth …
Role of staging laparoscopy for gastric cancer patients.
Fukagawa T. Fukagawa T. Ann Gastroenterol Surg. 2019 Aug 21;3(5):496-505. doi: 10.1002/ags3.12283. eCollection 2019 Sep. Ann Gastroenterol Surg. 2019. PMID: 31549009 Free PMC article. Review.
(i) What is an adequate indication for SL? (ii) How do you carry out SL? (iii) Does SL provide accurate information about peritoneal dissemination? (iv) Is the yield of SL different by tumor location? (v) Is SL a safe procedure? (vi) Is "repeat …
(i) What is an adequate indication for SL? (ii) How do you carry out SL? (iii) Does SL provide accurate information abo …
Sl-lncRNA15492 interacts with Sl-miR482a and affects Solanum lycopersicum immunity against Phytophthora infestans.
Jiang N, Cui J, Hou X, Yang G, Xiao Y, Han L, Meng J, Luan Y. Jiang N, et al. Plant J. 2020 Aug;103(4):1561-1574. doi: 10.1111/tpj.14847. Epub 2020 Jun 25. Plant J. 2020. PMID: 32432801 Free article.
Sl-lncRNA15492 inhibited the expression of mature Sl-miR482a, whose precursor was located within the antisense sequence of Sl-lncRNA15492. Further degradome analysis and additional RLM-5' RACE experiments verified that mature Sl-miR482a could also clea …
Sl-lncRNA15492 inhibited the expression of mature Sl-miR482a, whose precursor was located within the antisense sequence of …
62,286 results
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