Kong LR - Search Results

1

Anti-malarial drug artesunate attenuates experimental allergic asthma via inhibition of the phosphoinositide 3-kinase/Akt pathway.

Cheng C, Ho WE, Goh FY, Guan SP, Kong LR, Lai WQ, Leung BP, Wong WS. Cheng C, et al. Among authors: kong lr. PLoS One. 2011;6(6):e20932. doi: 10.1371/journal.pone.0020932. Epub 2011 Jun 9. PLoS One. 2011. PMID: 21695271 Free PMC article.

2

Protective role of 14-deoxy-11,12-didehydroandrographolide, a noncytotoxic analogue of andrographolide, in allergic airway inflammation.

Guan SP, Kong LR, Cheng C, Lim JC, Wong WS. Guan SP, et al. Among authors: kong lr. J Nat Prod. 2011 Jun 24;74(6):1484-90. doi: 10.1021/np2002572. Epub 2011 May 20. J Nat Prod. 2011. PMID: 21598983

3

MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma.

Kong LR, Chua KN, Sim WJ, Ng HC, Bi C, Ho J, Nga ME, Pang YH, Ong WR, Soo RA, Huynh H, Chng WJ, Thiery JP, Goh BC. Kong LR, et al. Mol Cancer Ther. 2015 Jul;14(7):1750-60. doi: 10.1158/1535-7163.MCT-15-0062. Epub 2015 May 4. Mol Cancer Ther. 2015. PMID: 25939760

4

Combinatorial treatment using targeted MEK and SRC inhibitors synergistically abrogates tumor cell growth and induces mesenchymal-epithelial transition in non-small-cell lung carcinoma.

Chua KN, Kong LR, Sim WJ, Ng HC, Ong WR, Thiery JP, Huynh H, Goh BC. Chua KN, et al. Among authors: kong lr. Oncotarget. 2015 Oct 6;6(30):29991-30005. doi: 10.18632/oncotarget.5031. Oncotarget. 2015. PMID: 26358373 Free PMC article.

5

Phase I and biomarker study of OPB-51602, a novel signal transducer and activator of transcription (STAT) 3 inhibitor, in patients with refractory solid malignancies.

Wong AL, Soo RA, Tan DS, Lee SC, Lim JS, Marban PC, Kong LR, Lee YJ, Wang LZ, Thuya WL, Soong R, Yee MQ, Chin TM, Cordero MT, Asuncion BR, Pang B, Pervaiz S, Hirpara JL, Sinha A, Xu WW, Yuasa M, Tsunoda T, Motoyama M, Yamauchi T, Goh BC. Wong AL, et al. Among authors: kong lr. Ann Oncol. 2015 May;26(5):998-1005. doi: 10.1093/annonc/mdv026. Epub 2015 Jan 21. Ann Oncol. 2015. PMID: 25609248 Free article. Clinical Trial.

6

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling.

Wang L, Syn NL, Subhash VV, Any Y, Thuya WL, Cheow ESH, Kong L, Yu F, Peethala PC, Wong AL, Laljibhai HJ, Chinnathambi A, Ong PS, Ho PC, Sethi G, Yong WP, Goh BC. Wang L, et al. Cancer Lett. 2018 Mar 28;417:152-160. doi: 10.1016/j.canlet.2017.12.030. Epub 2018 Jan 4. Cancer Lett. 2018. PMID: 29306016

7

Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance.

Hirpara J, Eu JQ, Tan JKM, Wong AL, Clement MV, Kong LR, Ohi N, Tsunoda T, Qu J, Goh BC, Pervaiz S. Hirpara J, et al. Among authors: kong lr. Redox Biol. 2019 Jul;25:101076. doi: 10.1016/j.redox.2018.101076. Epub 2018 Dec 17. Redox Biol. 2019. PMID: 30642723 Free PMC article.

8

A common MET polymorphism harnesses HER2 signaling to drive aggressive squamous cell carcinoma.

Kong LR, Mohamed Salleh NAB, Ong RW, Tan TZ, Syn NL, Goh RM, Fhu CW, Tan DSW, Iyer NG, Kannan S, Verma CS, Lim YC, Soo R, Ho J, Huang Y, Lim JSJ, Yan BJ, Nga ME, Lim SG, Koeffler HP, Lee SC, Kappei D, Hung HT, Goh BC. Kong LR, et al. Nat Commun. 2020 Mar 25;11(1):1556. doi: 10.1038/s41467-020-15318-5. Nat Commun. 2020. PMID: 32214092 Free PMC article.

9

Sustained IKKβ phosphorylation and NF-κB activation by superoxide-induced peroxynitrite-mediated nitrotyrosine modification of B56γ3 and PP2A inactivation.

Yee YH, Chong SJF, Kong LR, Goh BC, Pervaiz S. Yee YH, et al. Among authors: kong lr. Redox Biol. 2021 May;41:101834. doi: 10.1016/j.redox.2020.101834. Epub 2020 Dec 18. Redox Biol. 2021. PMID: 33838472 Free PMC article.

10

Targeting Metabolism in Cancer Cells and the Tumour Microenvironment for Cancer Therapy.

Li J, Eu JQ, Kong LR, Wang L, Lim YC, Goh BC, Wong ALA. Li J, et al. Among authors: kong lr. Molecules. 2020 Oct 20;25(20):4831. doi: 10.3390/molecules25204831. Molecules. 2020. PMID: 33092283 Free PMC article. Review.

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