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Page 1
Interferon-gamma regulation of interleukin 6 in monocytic cells.
Biondillo DE, Konicek SA, Iwamoto GK. Biondillo DE, et al. Among authors: konicek sa. Am J Physiol. 1994 Nov;267(5 Pt 1):L564-8. doi: 10.1152/ajplung.1994.267.5.L564. Am J Physiol. 1994. PMID: 7526705
Cytomegalovirus immediate early genes upregulate interleukin-6 gene expression.
Iwamoto GK, Konicek SA. Iwamoto GK, et al. Among authors: konicek sa. J Investig Med. 1997 Apr;45(4):175-82. J Investig Med. 1997. PMID: 9154298
Modulation of accessory cell function and interleukin-6 production by the HIV-1 tat gene.
Iwamoto GK, Konicek SA, Twigg HL 3rd. Iwamoto GK, et al. Among authors: konicek sa. Am J Respir Cell Mol Biol. 1994 May;10(5):580-5. doi: 10.1165/ajrcmb.10.5.8179923. Am J Respir Cell Mol Biol. 1994. PMID: 8179923
Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Cancer Xenograft Model.
Fales KR, Njoroge FG, Brooks HB, Thibodeaux S, Torrado A, Si C, Toth JL, Mc Cowan JR, Roth KD, Thrasher KJ, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Margolis BJ, Wu Z, Wang Y, Atwell S, Wang J, Hui YH, Meier TI, Konicek SA, Geeganage S. Fales KR, et al. Among authors: konicek sa. J Med Chem. 2017 Dec 14;60(23):9599-9616. doi: 10.1021/acs.jmedchem.7b01046. Epub 2017 Nov 9. J Med Chem. 2017. PMID: 29072452
Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models.
Brooks HB, Meier TI, Geeganage S, Fales KR, Thrasher KJ, Konicek SA, Spencer CD, Thibodeaux S, Foreman RT, Hui YH, Roth KD, Qian YW, Wang T, Luo S, Torrado A, Si C, Toth JL, Mc Cowan JR, Frimpong K, Lee MR, Dally RD, Shepherd TA, Durham TB, Wang Y, Wu Z, Iversen PW, Njoroge FG. Brooks HB, et al. Among authors: konicek sa. Sci Rep. 2018 Oct 18;8(1):15458. doi: 10.1038/s41598-018-33453-4. Sci Rep. 2018. PMID: 30337562 Free PMC article.
Pak-1 expression increases with progression of colorectal carcinomas to metastasis.
Carter JH, Douglass LE, Deddens JA, Colligan BM, Bhatt TR, Pemberton JO, Konicek S, Hom J, Marshall M, Graff JR. Carter JH, et al. Among authors: konicek s. Clin Cancer Res. 2004 May 15;10(10):3448-56. doi: 10.1158/1078-0432.CCR-03-0210. Clin Cancer Res. 2004. PMID: 15161701
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