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Establishment and characterization of a human acute monocytic leukemia cell line (THP-1).
Tsuchiya S, Yamabe M, Yamaguchi Y, Kobayashi Y, Konno T, Tada K. Tsuchiya S, et al. Among authors: konno t. Int J Cancer. 1980 Aug;26(2):171-6. doi: 10.1002/ijc.2910260208. Int J Cancer. 1980. PMID: 6970727
The monocytic nature of the cell line was characterized by: (1) the presence of alpha-naphthyl butyrate esterase activities which could be inhibited by NaF; (2) lysozyme production; (3) the phagocytosis of latex particles and sensitized sheep erythrocytes; and (4) the ability to …
The monocytic nature of the cell line was characterized by: (1) the presence of alpha-naphthyl butyrate esterase activities which could be i …
Identification of a highly specific surface marker of T-cell acute lymphoblastic leukemia and neuroblastoma as a new member of the transmembrane 4 superfamily.
Takagi S, Fujikawa K, Imai T, Fukuhara N, Fukudome K, Minegishi M, Tsuchiya S, Konno T, Hinuma Y, Yoshie O. Takagi S, et al. Among authors: konno t. Int J Cancer. 1995 May 29;61(5):706-15. doi: 10.1002/ijc.2910610519. Int J Cancer. 1995. PMID: 7768645
Five monoclonal antibodies detected a surface antigen expressed exclusively on T-cell acute lymphoblastic leukemia (T-ALL) in a panel of 45 human hematopoietic cell lines, including T-cell lines derived from adult T-cell leukemia and those established …
Five monoclonal antibodies detected a surface antigen expressed exclusively on T-cell acute lymphoblastic leukemia (T-ALL) in …
Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester.
Tsuchiya S, Kobayashi Y, Goto Y, Okumura H, Nakae S, Konno T, Tada K. Tsuchiya S, et al. Among authors: konno t. Cancer Res. 1982 Apr;42(4):1530-6. Cancer Res. 1982. PMID: 6949641
Characterization of a precursor T-cell line (THP-6) with rearranged T-cell receptor beta chain gene.
Minegishi M, Tsuchiya S, Minegishi N, Yoshie O, Nakamura M, Konno T. Minegishi M, et al. Among authors: konno t. Leuk Res. 1988;12(3):227-32. doi: 10.1016/0145-2126(88)90140-3. Leuk Res. 1988. PMID: 3130528
A previously established human leukemia cell line, designated THP-6, was further characterized with respect to cell surface antigen expression and immunoglobulin(Ig) and T-cell receptor(TCR) gene status. ...These results, in agreement with its phenotype, confirmed that THP …
A previously established human leukemia cell line, designated THP-6, was further characterized with respect to cell surface antigen expressi …
Expression of GATA transcription factors in myelogenous and lymphoblastic leukemia cells.
Minegishi N, Morita S, Minegishi M, Tsuchiya S, Konno T, Hayashi N, Yamamoto M. Minegishi N, et al. Among authors: konno t. Int J Hematol. 1997 Apr;65(3):239-49. doi: 10.1016/s0925-5710(96)00553-1. Int J Hematol. 1997. PMID: 9114595
GATA-3 is found exclusively in T cells of hematopoietic lineage. To clarify whether these expression profiles are preserved or changed during the development of malignancies, we analyzed the expression of GATA factors in the blasts from leukemic children. ...GATA-3 mRNA wa …
GATA-3 is found exclusively in T cells of hematopoietic lineage. To clarify whether these expression profiles are preserved or change …
Cell surface c-kit receptors in human leukemia cell lines and pediatric leukemia: selective preservation of c-kit expression on megakaryoblastic cell lines during adaptation to in vitro culture.
Morita S, Tsuchiya S, Fujie H, Itano M, Ohashi Y, Minegishi M, Imaizumi M, Endo M, Takano N, Konno T. Morita S, et al. Among authors: konno t. Leukemia. 1996 Jan;10(1):102-5. Leukemia. 1996. PMID: 8558913
Functional and molecular characteristics of acute lymphoblastic leukemia cells with a mature T-cell phenotype from a patient with ataxia telangiectasia.
Minegishi M, Tsuchiya S, Minegishi N, Nakamura M, Abo T, Inaba T, Konno T. Minegishi M, et al. Among authors: konno t. Leukemia. 1991 Jan;5(1):88-9. Leukemia. 1991. PMID: 1999961
A 12-year-old male patient with ataxia telangiectasia developed an acute lymphoblastic leukemia of T-cell phenotype. The lymphoblasts showed uniform surface expression of CD3, CD7, CD8, and T-cell receptor (TCR) alpha/beta chains, positive immunofluorescent staining …
A 12-year-old male patient with ataxia telangiectasia developed an acute lymphoblastic leukemia of T-cell phenotype. The lymphoblasts …
Isolation and characterization of two monoclonal antibodies that recognize different epitopes of the human c-kit receptor.
Morita S, Tsuchiya S, Fujie H, Itano M, Ohashi Y, Minegishi M, Konno T. Morita S, et al. Among authors: konno t. Tohoku J Exp Med. 1996 Feb;178(2):187-98. doi: 10.1620/tjem.178.187. Tohoku J Exp Med. 1996. PMID: 8727700
Subacute panencephalitis associated with chronic graft-versus-host disease.
Iwasaki Y, Sako K, Ohara Y, Miyazawa M, Minegishi M, Tsuchiya S, Konno T. Iwasaki Y, et al. Among authors: konno t. Acta Neuropathol. 1993;85(5):566-72. doi: 10.1007/BF00230498. Acta Neuropathol. 1993. PMID: 8493865
Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT.
Asada H, Ishii N, Sasaki Y, Endo K, Kasai H, Tanaka N, Takeshita T, Tsuchiya S, Konno T, Sugamura K. Asada H, et al. Among authors: konno t. J Exp Med. 1999 May 3;189(9):1383-90. doi: 10.1084/jem.189.9.1383. J Exp Med. 1999. PMID: 10224278 Free PMC article.
Expression of Grf40 is predominant in hematopoietic cells, particularly T cells. Grf40 binds to the SH2 domain-containing leukocyte protein of 76 kD (SLP-76) via its SH3 domain more tightly than Grb2. Incidentally, Grf40 binds to linker for activation of T cells (LA …
Expression of Grf40 is predominant in hematopoietic cells, particularly T cells. Grf40 binds to the SH2 domain-containing leukocyte p …
1,043 results
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