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Year Number of Results
2011 1
2012 1
2014 2
2015 2
2016 1
2017 2
2018 6
2019 2
2020 9
2021 14
2022 9
2023 14
2024 6
2025 9

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72 results

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Page 1
Actin cytoskeleton remodeling primes RIG-I-like receptor activation.
Acharya D, Reis R, Volcic M, Liu G, Wang MK, Chia BS, Nchioua R, Groß R, Münch J, Kirchhoff F, Sparrer KMJ, Gack MU. Acharya D, et al. Among authors: sparrer kmj. Cell. 2022 Sep 15;185(19):3588-3602.e21. doi: 10.1016/j.cell.2022.08.011. Cell. 2022. PMID: 36113429 Free PMC article.
Regulation of STING activity in DNA sensing by ISG15 modification.
Lin C, Kuffour EO, Fuchs NV, Gertzen CGW, Kaiser J, Hirschenberger M, Tang X, Xu HC, Michel O, Tao R, Haase A, Martin U, Kurz T, Drexler I, Görg B, Lang PA, Luedde T, Sparrer KMJ, Gohlke H, König R, Münk C. Lin C, et al. Among authors: sparrer kmj. Cell Rep. 2023 Nov 28;42(11):113277. doi: 10.1016/j.celrep.2023.113277. Epub 2023 Oct 20. Cell Rep. 2023. PMID: 37864791 Free article.
ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.
Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, Sparrer KMJ. Hirschenberger M, et al. Among authors: sparrer kmj. Nat Commun. 2023 Nov 1;14(1):6770. doi: 10.1038/s41467-023-42150-4. Nat Commun. 2023. PMID: 37914730 Free PMC article.
TRIM23 mediates virus-induced autophagy via activation of TBK1.
Sparrer KMJ, Gableske S, Zurenski MA, Parker ZM, Full F, Baumgart GJ, Kato J, Pacheco-Rodriguez G, Liang C, Pornillos O, Moss J, Vaughan M, Gack MU. Sparrer KMJ, et al. Nat Microbiol. 2017 Nov;2(11):1543-1557. doi: 10.1038/s41564-017-0017-2. Epub 2017 Sep 4. Nat Microbiol. 2017. PMID: 28871090 Free PMC article.
Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2.
Thoms M, Buschauer R, Ameismeier M, Koepke L, Denk T, Hirschenberger M, Kratzat H, Hayn M, Mackens-Kiani T, Cheng J, Straub JH, Stürzel CM, Fröhlich T, Berninghausen O, Becker T, Kirchhoff F, Sparrer KMJ, Beckmann R. Thoms M, et al. Among authors: sparrer kmj. Science. 2020 Sep 4;369(6508):1249-1255. doi: 10.1126/science.abc8665. Epub 2020 Jul 17. Science. 2020. PMID: 32680882 Free PMC article.
Acetylation of the NS3 helicase by KAT5γ is essential for flavivirus replication.
Serman T, Chiang C, Liu G, Sayyad Z, Pandey S, Volcic M, Lee H, Muppala S, Acharya D, Goins C, Stauffer SR, Sparrer KMJ, Gack MU. Serman T, et al. Among authors: sparrer kmj. Cell Host Microbe. 2023 Aug 9;31(8):1317-1330.e10. doi: 10.1016/j.chom.2023.06.013. Epub 2023 Jul 20. Cell Host Microbe. 2023. PMID: 37478852 Free PMC article.
Phosphatidylserine-exposing extracellular vesicles in body fluids are an innate defence against apoptotic mimicry viral pathogens.
Groß R, Reßin H, von Maltitz P, Albers D, Schneider L, Bley H, Hoffmann M, Cortese M, Gupta D, Deniz M, Choi JY, Jansen J, Preußer C, Seehafer K, Pöhlmann S, Voelker DR, Goffinet C, Pogge-von Strandmann E, Bunz U, Bartenschlager R, El Andaloussi S, Sparrer KMJ, Herker E, Becker S, Kirchhoff F, Münch J, Müller JA. Groß R, et al. Among authors: sparrer kmj. Nat Microbiol. 2024 Apr;9(4):905-921. doi: 10.1038/s41564-024-01637-6. Epub 2024 Mar 25. Nat Microbiol. 2024. PMID: 38528146 Free PMC article.
TRIM23 mediates cGAS-induced autophagy in anti-HSV defense.
Acharya D, Sayyad Z, Hoenigsperger H, Hirschenberger M, Zurenski M, Balakrishnan K, Zhu J, Gableske S, Kato J, Zhang SY, Casanova JL, Moss J, Sparrer KMJ, Gack MU. Acharya D, et al. Among authors: sparrer kmj. Nat Commun. 2025 May 13;16(1):4418. doi: 10.1038/s41467-025-59338-5. Nat Commun. 2025. PMID: 40360474 Free PMC article.
CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins.
Hoenigsperger H, Koepke L, Acharya D, Hunszinger V, Freisem D, Grenzner A, Wiese S, Kirchhoff F, Gack MU, Sparrer KMJ. Hoenigsperger H, et al. Among authors: sparrer kmj. Autophagy. 2024 May;20(5):994-1014. doi: 10.1080/15548627.2023.2281128. Epub 2023 Nov 17. Autophagy. 2024. PMID: 37938186 Free PMC article.
72 results