Kontaridis MI - Search Results

1

Resveratrol inhibits angiotensin II- and epidermal growth factor-mediated Akt activation: role of Gab1 and Shp2.

Haider UG, Roos TU, Kontaridis MI, Neel BG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Haider UG, et al. Among authors: kontaridis mi. Mol Pharmacol. 2005 Jul;68(1):41-8. doi: 10.1124/mol.104.005421. Epub 2005 Apr 22. Mol Pharmacol. 2005. PMID: 15849355

2

Shp2 regulates SRC family kinase activity and Ras/Erk activation by controlling Csk recruitment.

Zhang SQ, Yang W, Kontaridis MI, Bivona TG, Wen G, Araki T, Luo J, Thompson JA, Schraven BL, Philips MR, Neel BG. Zhang SQ, et al. Among authors: kontaridis mi. Mol Cell. 2004 Feb 13;13(3):341-55. doi: 10.1016/s1097-2765(04)00050-4. Mol Cell. 2004. PMID: 14967142 Free article.

3

PTPN11 (Shp2) mutations in LEOPARD syndrome have dominant negative, not activating, effects.

Kontaridis MI, Swanson KD, David FS, Barford D, Neel BG. Kontaridis MI, et al. J Biol Chem. 2006 Mar 10;281(10):6785-92. doi: 10.1074/jbc.M513068200. Epub 2005 Dec 23. J Biol Chem. 2006. PMID: 16377799 Free article.

4

Gain-of-function mutations in the gene encoding the tyrosine phosphatase SHP2 induce hydrocephalus in a catalytically dependent manner.

Zheng H, Yu WM, Waclaw RR, Kontaridis MI, Neel BG, Qu CK. Zheng H, et al. Among authors: kontaridis mi. Sci Signal. 2018 Mar 20;11(522):eaao1591. doi: 10.1126/scisignal.aao1591. Sci Signal. 2018. PMID: 29559584 Free PMC article.

5

Deletion of Ptpn11 (Shp2) in cardiomyocytes causes dilated cardiomyopathy via effects on the extracellular signal-regulated kinase/mitogen-activated protein kinase and RhoA signaling pathways.

Kontaridis MI, Yang W, Bence KK, Cullen D, Wang B, Bodyak N, Ke Q, Hinek A, Kang PM, Liao R, Neel BG. Kontaridis MI, et al. Circulation. 2008 Mar 18;117(11):1423-35. doi: 10.1161/CIRCULATIONAHA.107.728865. Epub 2008 Mar 3. Circulation. 2008. PMID: 18316486 Free PMC article.

6

Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation.

Marin TM, Keith K, Davies B, Conner DA, Guha P, Kalaitzidis D, Wu X, Lauriol J, Wang B, Bauer M, Bronson R, Franchini KG, Neel BG, Kontaridis MI. Marin TM, et al. Among authors: kontaridis mi. J Clin Invest. 2011 Mar;121(3):1026-43. doi: 10.1172/JCI44972. Epub 2011 Feb 21. J Clin Invest. 2011. PMID: 21339643 Free PMC article.

7

Stops along the RAS pathway in human genetic disease.

Bentires-Alj M, Kontaridis MI, Neel BG. Bentires-Alj M, et al. Among authors: kontaridis mi. Nat Med. 2006 Mar;12(3):283-5. doi: 10.1038/nm0306-283. Nat Med. 2006. PMID: 16520774 No abstract available.

8

Phosphatase-dependent and -independent functions of Shp2 in neural crest cells underlie LEOPARD syndrome pathogenesis.

Stewart RA, Sanda T, Widlund HR, Zhu S, Swanson KD, Hurley AD, Bentires-Alj M, Fisher DE, Kontaridis MI, Look AT, Neel BG. Stewart RA, et al. Among authors: kontaridis mi. Dev Cell. 2010 May 18;18(5):750-62. doi: 10.1016/j.devcel.2010.03.009. Dev Cell. 2010. PMID: 20493809 Free PMC article.

9

Role of SHP-2 in fibroblast growth factor receptor-mediated suppression of myogenesis in C2C12 myoblasts.

Kontaridis MI, Liu X, Zhang L, Bennett AM. Kontaridis MI, et al. Mol Cell Biol. 2002 Jun;22(11):3875-91. doi: 10.1128/MCB.22.11.3875-3891.2002. Mol Cell Biol. 2002. PMID: 11997521 Free PMC article.

10

The third international meeting on genetic disorders in the RAS/MAPK pathway: towards a therapeutic approach.

Korf B, Ahmadian R, Allanson J, Aoki Y, Bakker A, Wright EB, Denger B, Elgersma Y, Gelb BD, Gripp KW, Kerr B, Kontaridis M, Lazaro C, Linardic C, Lozano R, MacRae CA, Messiaen L, Mulero-Navarro S, Neel B, Plotkin S, Rauen KA, Roberts A, Silva AJ, Sittampalam SG, Zhang C, Schoyer L. Korf B, et al. Am J Med Genet A. 2015 Aug;167A(8):1741-6. doi: 10.1002/ajmg.a.37089. Epub 2015 Apr 21. Am J Med Genet A. 2015. PMID: 25900621 Free PMC article.

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