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Current Status and Future Prospects of Small-molecule Protein-protein Interaction (PPI) Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
Melagraki G, Leonis G, Ntougkos E, Rinotas V, Papaneophytou C, Mavromoustakos T, Kontopidis G, Douni E, Kollias G, Afantitis A. Melagraki G, et al. Among authors: kontopidis g. Curr Top Med Chem. 2018;18(8):661-673. doi: 10.2174/1568026618666180607084430. Curr Top Med Chem. 2018. PMID: 29875003 Review.
Cheminformatics-aided discovery of small-molecule Protein-Protein Interaction (PPI) dual inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-κB Ligand (RANKL).
Melagraki G, Ntougkos E, Rinotas V, Papaneophytou C, Leonis G, Mavromoustakos T, Kontopidis G, Douni E, Afantitis A, Kollias G. Melagraki G, et al. Among authors: kontopidis g. PLoS Comput Biol. 2017 Apr 20;13(4):e1005372. doi: 10.1371/journal.pcbi.1005372. eCollection 2017 Apr. PLoS Comput Biol. 2017. PMID: 28426652 Free PMC article.
Rationally designed less toxic SPD-304 analogs and preliminary evaluation of their TNF inhibitory effects.
Alexiou P, Papakyriakou A, Ntougkos E, Papaneophytou CP, Liepouri F, Mettou A, Katsoulis I, Maranti A, Tsiliouka K, Strongilos A, Chaitidou S, Douni E, Kontopidis G, Kollias G, Couladouros E, Eliopoulos E. Alexiou P, et al. Among authors: kontopidis g. Arch Pharm (Weinheim). 2014 Nov;347(11):798-805. doi: 10.1002/ardp.201400198. Epub 2014 Aug 27. Arch Pharm (Weinheim). 2014. PMID: 25160057
49 results