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Specificity mapping of HIV-1 protease by reduced bond inhibitors.
Majer P, Urban J, Gregorová E, Konvalinka J, Novek P, Stehlíková J, Andreánsky M, Sedlácek J, Strop P. Majer P, et al. Among authors: konvalinka j. Arch Biochem Biophys. 1993 Jul;304(1):1-8. doi: 10.1006/abbi.1993.1314. Arch Biochem Biophys. 1993. PMID: 8323274
Configurations of diastereomeric hydroxyethylene isosteres strongly affect biological activities of a series of specific inhibitors of human-immunodeficiency-virus proteinase.
Konvalinka J, Litera J, Weber J, Vondrásek J, Hradílek M, Soucek M, Pichová I, Majer P, Strop P, Sedlácek J, Heuser AM, Kottler H, Kräusslich HG. Konvalinka J, et al. Eur J Biochem. 1997 Dec 1;250(2):559-66. doi: 10.1111/j.1432-1033.1997.0559a.x. Eur J Biochem. 1997. PMID: 9428710 Free article.
Unusual binding mode of an HIV-1 protease inhibitor explains its potency against multi-drug-resistant virus strains.
Weber J, Mesters JR, Lepsík M, Prejdová J, Svec M, Sponarová J, Mlcochová P, Skalická K, Strísovský K, Uhlíková T, Soucek M, Machala L, Stanková M, Vondrásek J, Klimkait T, Kraeusslich HG, Hilgenfeld R, Konvalinka J. Weber J, et al. Among authors: konvalinka j. J Mol Biol. 2002 Dec 6;324(4):739-54. doi: 10.1016/s0022-2836(02)01139-7. J Mol Biol. 2002. PMID: 12460574
144 results