Koo T - Search Results

1

Negative regulation-resistant p53 variant enhances oncolytic adenoviral gene therapy.

Koo T, Choi IK, Kim M, Lee JS, Oh E, Kim J, Yun CO. Koo T, et al. Hum Gene Ther. 2012 Jun;23(6):609-22. doi: 10.1089/hum.2011.114. Epub 2012 Feb 21. Hum Gene Ther. 2012. PMID: 22248367 Free PMC article.

2

ADP-overexpressing adenovirus elicits enhanced cytopathic effect by induction of apoptosis.

Yun CO, Kim E, Koo T, Kim H, Lee YS, Kim JH. Yun CO, et al. Among authors: koo t. Cancer Gene Ther. 2005 Jan;12(1):61-71. doi: 10.1038/sj.cgt.7700769. Cancer Gene Ther. 2005. PMID: 15375379

3

CRISPR-Cas12a with an oAd Induces Precise and Cancer-Specific Genomic Reprogramming of EGFR and Efficient Tumor Regression.

Yoon AR, Jung BK, Choi E, Chung E, Hong J, Kim JS, Koo T, Yun CO. Yoon AR, et al. Among authors: koo t. Mol Ther. 2020 Oct 7;28(10):2286-2296. doi: 10.1016/j.ymthe.2020.07.003. Epub 2020 Jul 3. Mol Ther. 2020. PMID: 32682455 Free PMC article.

4

Selective disruption of an oncogenic mutant allele by CRISPR/Cas9 induces efficient tumor regression.

Koo T, Yoon AR, Cho HY, Bae S, Yun CO, Kim JS. Koo T, et al. Nucleic Acids Res. 2017 Jul 27;45(13):7897-7908. doi: 10.1093/nar/gkx490. Nucleic Acids Res. 2017. PMID: 28575452 Free PMC article.

5

Delivery of AAV2/9-microdystrophin genes incorporating helix 1 of the coiled-coil motif in the C-terminal domain of dystrophin improves muscle pathology and restores the level of α1-syntrophin and α-dystrobrevin in skeletal muscles of mdx mice.

Koo T, Malerba A, Athanasopoulos T, Trollet C, Boldrin L, Ferry A, Popplewell L, Foster H, Foster K, Dickson G. Koo T, et al. Hum Gene Ther. 2011 Nov;22(11):1379-88. doi: 10.1089/hum.2011.020. Epub 2011 May 25. Hum Gene Ther. 2011. PMID: 21453126 Free PMC article.

6

Gene correction of a duchenne muscular dystrophy mutation by meganuclease-enhanced exon knock-in.

Popplewell L, Koo T, Leclerc X, Duclert A, Mamchaoui K, Gouble A, Mouly V, Voit T, Pâques F, Cédrone F, Isman O, Yáñez-Muñoz RJ, Dickson G. Popplewell L, et al. Among authors: koo t. Hum Gene Ther. 2013 Jul;24(7):692-701. doi: 10.1089/hum.2013.081. Hum Gene Ther. 2013. PMID: 23790397

7

Functional Rescue of Dystrophin Deficiency in Mice Caused by Frameshift Mutations Using Campylobacter jejuni Cas9.

Koo T, Lu-Nguyen NB, Malerba A, Kim E, Kim D, Cappellari O, Cho HY, Dickson G, Popplewell L, Kim JS. Koo T, et al. Mol Ther. 2018 Jun 6;26(6):1529-1538. doi: 10.1016/j.ymthe.2018.03.018. Epub 2018 Mar 30. Mol Ther. 2018. PMID: 29730196 Free PMC article.

8

Triple trans-splicing adeno-associated virus vectors capable of transferring the coding sequence for full-length dystrophin protein into dystrophic mice.

Koo T, Popplewell L, Athanasopoulos T, Dickson G. Koo T, et al. Hum Gene Ther. 2014 Feb;25(2):98-108. doi: 10.1089/hum.2013.164. Epub 2013 Dec 19. Hum Gene Ther. 2014. PMID: 24191945

9

Long-Term Effects of In Vivo Genome Editing in the Mouse Retina Using Campylobacter jejuni Cas9 Expressed via Adeno-Associated Virus.

Jo DH, Koo T, Cho CS, Kim JH, Kim JS, Kim JH. Jo DH, et al. Among authors: koo t. Mol Ther. 2019 Jan 2;27(1):130-136. doi: 10.1016/j.ymthe.2018.10.009. Epub 2018 Oct 17. Mol Ther. 2019. PMID: 30470629 Free PMC article.

10

Long-term functional adeno-associated virus-microdystrophin expression in the dystrophic CXMDj dog.

Koo T, Okada T, Athanasopoulos T, Foster H, Takeda S, Dickson G. Koo T, et al. J Gene Med. 2011 Sep;13(9):497-506. doi: 10.1002/jgm.1602. J Gene Med. 2011. PMID: 22144143

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