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Active site tightness and substrate fit in DNA replication.
Kool ET. Kool ET. Annu Rev Biochem. 2002;71:191-219. doi: 10.1146/annurev.biochem.71.110601.135453. Epub 2001 Nov 9. Annu Rev Biochem. 2002. PMID: 12045095 Review.
Origins of the large differences in stability of DNA and RNA helices: C-5 methyl and 2'-hydroxyl effects.
Wang S, Kool ET. Wang S, et al. Among authors: kool et. Biochemistry. 1995 Mar 28;34(12):4125-32. doi: 10.1021/bi00012a031. Biochemistry. 1995. PMID: 7535100
Origins of high sequence selectivity: a stopped-flow kinetics study of DNA/RNA hybridization by duplex- and triplex-forming oligonucleotides.
Wang S, Friedman AE, Kool ET. Wang S, et al. Among authors: kool et. Biochemistry. 1995 Aug 1;34(30):9774-84. doi: 10.1021/bi00030a015. Biochemistry. 1995. PMID: 7542923
Stabilities of nucleotide loops bridging the pyrimidine strands in DNA pyrimidine.purine.pyrimidine triplexes: special stability of the CTTTG loop.
Wang S, Booher MA, Kool ET. Wang S, et al. Among authors: kool et. Biochemistry. 1994 Apr 19;33(15):4639-44. doi: 10.1021/bi00181a026. Biochemistry. 1994. PMID: 8161520
The first and last nucleotides in the loop are varied, since stacking interactions may be strongest at these positions [Senior et al., 1988a; Senior, M., Jones, R. ...
The first and last nucleotides in the loop are varied, since stacking interactions may be strongest at these positions [Senior et al. …
Base pairing and steric interactions between pyrimidine strand bridging loops and the purine strand in DNA pyrimidine.purine.pyrimidine triplexes.
Booher MA, Wang S, Kool ET. Booher MA, et al. Among authors: kool et. Biochemistry. 1994 Apr 19;33(15):4645-51. doi: 10.1021/bi00181a027. Biochemistry. 1994. PMID: 8161521
Bimolecular triple-helical DNA complexes recently have found use in a new strategy for the recognition of single-stranded nucleic acids, in which circular (Kool, 1991; Prakash & Kool, 1992) or hairpin-shaped (Giovannangeli et al., 1991; D'Souza & K
Bimolecular triple-helical DNA complexes recently have found use in a new strategy for the recognition of single-stranded nucleic acids, in …
Non-hydrogen bonding 'terminator' nucleosides increase the 3'-end homogeneity of enzymatic RNA and DNA synthesis.
Moran S, Ren RX, Sheils CJ, Rumney S 4th, Kool ET. Moran S, et al. Among authors: kool et. Nucleic Acids Res. 1996 Jun 1;24(11):2044-52. doi: 10.1093/nar/24.11.2044. Nucleic Acids Res. 1996. PMID: 8668534 Free PMC article.
Circular oligonucleotides: new concepts in oligonucleotide design.
Kool ET. Kool ET. Annu Rev Biophys Biomol Struct. 1996;25:1-28. doi: 10.1146/annurev.bb.25.060196.000245. Annu Rev Biophys Biomol Struct. 1996. PMID: 8800462 Review.
Escherichia coli RNA polymerase activity observed using atomic force microscopy.
Kasas S, Thomson NH, Smith BL, Hansma HG, Zhu X, Guthold M, Bustamante C, Kool ET, Kashlev M, Hansma PK. Kasas S, et al. Among authors: kool et. Biochemistry. 1997 Jan 21;36(3):461-8. doi: 10.1021/bi9624402. Biochemistry. 1997. PMID: 9012661
A thymidine triphosphate shape analog lacking Watson-Crick pairing ability is replicated with high sequence selectivity.
Moran S, Ren RX, Kool ET. Moran S, et al. Among authors: kool et. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):10506-11. doi: 10.1073/pnas.94.20.10506. Proc Natl Acad Sci U S A. 1997. PMID: 9380669 Free PMC article.
Bi-stranded, multisite replication of a base pair between difluorotoluene and adenine: confirmation by 'inverse' sequencing.
Liu D, Moran S, Kool ET. Liu D, et al. Among authors: kool et. Chem Biol. 1997 Dec;4(12):919-26. doi: 10.1016/s1074-5521(97)90300-8. Chem Biol. 1997. PMID: 9427657
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