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Costimulation-adhesion blockade is superior to cyclosporine A and prednisone immunosuppressive therapy for preventing rejection of differentiated human embryonic stem cells following transplantation.
Huber BC, Ransohoff JD, Ransohoff KJ, Riegler J, Ebert A, Kodo K, Gong Y, Sanchez-Freire V, Dey D, Kooreman NG, Diecke S, Zhang WY, Odegaard J, Hu S, Gold JD, Robbins RC, Wu JC. Huber BC, et al. Among authors: kooreman ng. Stem Cells. 2013 Nov;31(11):2354-63. doi: 10.1002/stem.1501. Stem Cells. 2013. PMID: 24038578 Free PMC article.
Transplanted terminally differentiated induced pluripotent stem cells are accepted by immune mechanisms similar to self-tolerance.
de Almeida PE, Meyer EH, Kooreman NG, Diecke S, Dey D, Sanchez-Freire V, Hu S, Ebert A, Odegaard J, Mordwinkin NM, Brouwer TP, Lo D, Montoro DT, Longaker MT, Negrin RS, Wu JC. de Almeida PE, et al. Among authors: kooreman ng. Nat Commun. 2014 May 30;5:3903. doi: 10.1038/ncomms4903. Nat Commun. 2014. PMID: 24875164 Free PMC article.
Alloimmune Responses of Humanized Mice to Human Pluripotent Stem Cell Therapeutics.
Kooreman NG, de Almeida PE, Stack JP, Nelakanti RV, Diecke S, Shao NY, Swijnenburg RJ, Sanchez-Freire V, Matsa E, Liu C, Connolly AJ, Hamming JF, Quax PHA, Brehm MA, Greiner DL, Shultz LD, Wu JC. Kooreman NG, et al. Cell Rep. 2017 Aug 22;20(8):1978-1990. doi: 10.1016/j.celrep.2017.08.003. Cell Rep. 2017. PMID: 28834758 Free PMC article.
Preclinical derivation and imaging of autologously transplanted canine induced pluripotent stem cells.
Lee AS, Xu D, Plews JR, Nguyen PK, Nag D, Lyons JK, Han L, Hu S, Lan F, Liu J, Huang M, Narsinh KH, Long CT, de Almeida PE, Levi B, Kooreman N, Bangs C, Pacharinsak C, Ikeno F, Yeung AC, Gambhir SS, Robbins RC, Longaker MT, Wu JC. Lee AS, et al. J Biol Chem. 2011 Sep 16;286(37):32697-704. doi: 10.1074/jbc.M111.235739. Epub 2011 Jun 30. J Biol Chem. 2011. PMID: 21719696 Free PMC article.
Tracking gene and cell fate for therapeutic gain.
Kooreman NG, Ransohoff JD, Wu JC. Kooreman NG, et al. Nat Mater. 2014 Feb;13(2):106-9. doi: 10.1038/nmat3868. Nat Mater. 2014. PMID: 24452344 Free PMC article. Review.
20 results