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Selective Glucocorticoid Receptor Modulation Prevents and Reverses Nonalcoholic Fatty Liver Disease in Male Mice.
Koorneef LL, van den Heuvel JK, Kroon J, Boon MR, 't Hoen PAC, Hettne KM, van de Velde NM, Kolenbrander KB, Streefland TCM, Mol IM, Sips HCM, Kielbasa SM, Mei H, Belanoff JK, Pereira AM, Oosterveer MH, Hunt H, Rensen PCN, Meijer OC. Koorneef LL, et al. Endocrinology. 2018 Dec 1;159(12):3925-3936. doi: 10.1210/en.2018-00671. Endocrinology. 2018. PMID: 30321321
Glucocorticoid receptor modulators.
Meijer OC, Koorneef LL, Kroon J. Meijer OC, et al. Among authors: koorneef ll. Ann Endocrinol (Paris). 2018 Jun;79(3):107-111. doi: 10.1016/j.ando.2018.03.004. Epub 2018 May 3. Ann Endocrinol (Paris). 2018. PMID: 29731108 Review.
Corticosteroid Action in the Brain: The Potential of Selective Receptor Modulation.
Viho EMG, Buurstede JC, Mahfouz A, Koorneef LL, van Weert LTCM, Houtman R, Hunt HJ, Kroon J, Meijer OC. Viho EMG, et al. Among authors: koorneef ll. Neuroendocrinology. 2019;109(3):266-276. doi: 10.1159/000499659. Epub 2019 Mar 19. Neuroendocrinology. 2019. PMID: 30884490 Free PMC article. Review.
Twelve weeks of exenatide treatment increases [18F]fluorodeoxyglucose uptake by brown adipose tissue without affecting oxidative resting energy expenditure in nondiabetic males.
Janssen LGM, Nahon KJ, Bracké KFM, van den Broek D, Smit R, Sardjoe Mishre ASD, Koorneef LL, Martinez-Tellez B, Burakiewicz J, Kan HE, van Velden FHP, Pereira Arias-Bouda LM, de Geus-Oei LF, Berbée JFP, Jazet IM, Boon MR, Rensen PCN. Janssen LGM, et al. Among authors: koorneef ll. Metabolism. 2020 May;106:154167. doi: 10.1016/j.metabol.2020.154167. Epub 2020 Jan 23. Metabolism. 2020. PMID: 31982480 Free article. Clinical Trial.
A physiological glucocorticoid rhythm is an important regulator of brown adipose tissue function.
Kroon J, Schilperoort M, In Het Panhuis W, van den Berg R, van Doeselaar L, Verzijl CRC, van Trigt N, Mol IM, Sips HHCM, van den Heuvel JK, Koorneef LL, van der Sluis RJ, Fenzl A, Kiefer FW, Vettorazzi S, Tuckermann JP, Biermasz NR, Meijer OC, Rensen PCN, Kooijman S. Kroon J, et al. Among authors: koorneef ll. Mol Metab. 2021 May;47:101179. doi: 10.1016/j.molmet.2021.101179. Epub 2021 Feb 3. Mol Metab. 2021. PMID: 33548499 Free PMC article.
Hippocampal glucocorticoid target genes associated with enhancement of memory consolidation.
Buurstede JC, van Weert LTCM, Colucci P, Gentenaar M, Viho EMG, Koorneef LL, Schoonderwoerd RA, Lanooij SD, Moustakas I, Balog J, Mei H, Kielbasa SM, Campolongo P, Roozendaal B, Meijer OC. Buurstede JC, et al. Among authors: koorneef ll. Eur J Neurosci. 2022 May;55(9-10):2666-2683. doi: 10.1111/ejn.15226. Epub 2021 May 6. Eur J Neurosci. 2022. PMID: 33840130 Free PMC article.
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