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Aggresomes, inclusion bodies and protein aggregation.
Kopito RR. Kopito RR. Trends Cell Biol. 2000 Dec;10(12):524-30. doi: 10.1016/s0962-8924(00)01852-3. Trends Cell Biol. 2000. PMID: 11121744 Review.
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
Olzmann JA, Richter CM, Kopito RR. Olzmann JA, et al. Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1345-50. doi: 10.1073/pnas.1213738110. Epub 2013 Jan 7. Proc Natl Acad Sci U S A. 2013. PMID: 23297223 Free PMC article.
Fibrillar structure and charge determine the interaction of polyglutamine protein aggregates with the cell surface.
Trevino RS, Lauckner JE, Sourigues Y, Pearce MM, Bousset L, Melki R, Kopito RR. Trevino RS, et al. J Biol Chem. 2012 Aug 24;287(35):29722-8. doi: 10.1074/jbc.M112.372474. Epub 2012 Jun 29. J Biol Chem. 2012. PMID: 22753412 Free PMC article.
Prion-Like Characteristics of Polyglutamine-Containing Proteins.
Pearce MMP, Kopito RR. Pearce MMP, et al. Among authors: kopito rr. Cold Spring Harb Perspect Med. 2018 Feb 1;8(2):a024257. doi: 10.1101/cshperspect.a024257. Cold Spring Harb Perspect Med. 2018. PMID: 28096245 Free PMC article. Review.
Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease.
Bersuker K, Hipp MS, Calamini B, Morimoto RI, Kopito RR. Bersuker K, et al. J Biol Chem. 2013 Aug 16;288(33):23633-8. doi: 10.1074/jbc.C113.481945. Epub 2013 Jul 9. J Biol Chem. 2013. PMID: 23839939 Free PMC article.
Protein misfolding specifies recruitment to cytoplasmic inclusion bodies.
Bersuker K, Brandeis M, Kopito RR. Bersuker K, et al. J Cell Biol. 2016 Apr 25;213(2):229-41. doi: 10.1083/jcb.201511024. J Cell Biol. 2016. PMID: 27114501 Free PMC article.
Ron R. Kopito: Unfolding the Secrets of Protein Aggregation.
Kopito RR. Kopito RR. Trends Cell Biol. 2016 Aug;26(8):559-560. doi: 10.1016/j.tcb.2016.05.001. Epub 2016 May 27. Trends Cell Biol. 2016. PMID: 27238420 No abstract available.
Genome-wide CRISPR Analysis Identifies Substrate-Specific Conjugation Modules in ER-Associated Degradation.
Leto DE, Morgens DW, Zhang L, Walczak CP, Elias JE, Bassik MC, Kopito RR. Leto DE, et al. Among authors: kopito rr. Mol Cell. 2019 Jan 17;73(2):377-389.e11. doi: 10.1016/j.molcel.2018.11.015. Epub 2018 Dec 20. Mol Cell. 2019. PMID: 30581143 Free PMC article.
Unassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrate.
Tyler RE, Pearce MM, Shaler TA, Olzmann JA, Greenblatt EJ, Kopito RR. Tyler RE, et al. Mol Biol Cell. 2012 Dec;23(24):4668-78. doi: 10.1091/mbc.E12-06-0428. Epub 2012 Oct 24. Mol Biol Cell. 2012. PMID: 23097496 Free PMC article.
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