Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

190 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Autoantigen specific T cells inhibit glutamate uptake in astrocytes by decreasing expression of astrocytic glutamate transporter GLAST: a mechanism mediated by tumor necrosis factor-alpha.
Korn T, Magnus T, Jung S. Korn T, et al. FASEB J. 2005 Nov;19(13):1878-80. doi: 10.1096/fj.05-3748fje. Epub 2005 Aug 25. FASEB J. 2005. PMID: 16123171
We asked what might be the basis of glutamate accumulation in T cell triggered autoimmune inflammation. In vitro, coculture of primary rat astrocytes with activated myelin basic protein (MBP)-specific T cells resulted in a decrease of astrocytic glutamate uptake rat …
We asked what might be the basis of glutamate accumulation in T cell triggered autoimmune inflammation. In vitro, coculture of primar …
Dynamics of antigen-specific regulatory T-cells in the context of autoimmunity.
Korn T, Oukka M. Korn T, et al. Semin Immunol. 2007 Aug;19(4):272-8. doi: 10.1016/j.smim.2007.03.001. Epub 2007 Apr 16. Semin Immunol. 2007. PMID: 17434316 Review.
Naturally occurring regulatory T-cells (nT-reg) are crucial in preventing generalized autoimmunity. However, antigen-specific T-reg responses during organ-specific autoimmunity have not been characterized until recently when novel tools including MHC class II-tetram …
Naturally occurring regulatory T-cells (nT-reg) are crucial in preventing generalized autoimmunity. However, antigen-specific T
Autoimmune modulation of astrocyte-mediated homeostasis.
Korn T, Rao M, Magnus T. Korn T, et al. Neuromolecular Med. 2007;9(1):1-16. doi: 10.1385/nmm:9:1:1. Neuromolecular Med. 2007. PMID: 17114820 Review.
In neuroinflammation, astrocytes have classically been regarded as unimportant since their capacity to present antigen to T cells is limited and has been questioned in vivo. ...
In neuroinflammation, astrocytes have classically been regarded as unimportant since their capacity to present antigen to T cells is …
The dynamics of effector T cells and Foxp3+ regulatory T cells in the promotion and regulation of autoimmune encephalomyelitis.
Korn T, Anderson AC, Bettelli E, Oukka M. Korn T, et al. J Neuroimmunol. 2007 Nov;191(1-2):51-60. doi: 10.1016/j.jneuroim.2007.09.009. Epub 2007 Oct 3. J Neuroimmunol. 2007. PMID: 17916388 Free PMC article. Review.
The Th1/Th2 paradigm of T helper cell subsets had to be revised when IL-17 producing T cells (Th17) were identified as a distinct T helper cell lineage. ...Here, we review recent findings of how responses of effector T cells and T-reg cells with …
The Th1/Th2 paradigm of T helper cell subsets had to be revised when IL-17 producing T cells (Th17) were identified as a disti …
Th17 cells in central nervous system autoimmunity.
Sie C, Korn T, Mitsdoerffer M. Sie C, et al. Exp Neurol. 2014 Dec;262 Pt A:18-27. doi: 10.1016/j.expneurol.2014.03.009. Epub 2014 Mar 27. Exp Neurol. 2014. PMID: 24681001 Review.
Its animal model experimental autoimmune encephalomyelitis (EAE) has been instrumental in defining the features of the novel T helper cell subset Th17. ...Here, we review the current knowledge on Th17 cells and their contribution to the immunopathology in EAE and MS, cover …
Its animal model experimental autoimmune encephalomyelitis (EAE) has been instrumental in defining the features of the novel T helper …
Cytokines and effector T cell subsets causing autoimmune CNS disease.
Petermann F, Korn T. Petermann F, et al. FEBS Lett. 2011 Dec 1;585(23):3747-57. doi: 10.1016/j.febslet.2011.03.064. Epub 2011 Apr 6. FEBS Lett. 2011. PMID: 21477588 Review.
EAE was also very useful to refute the idea that IFN-γ producing T helper type 1 (Th1) cells were the sole players within the pathogenic T cell response. ...Here, we will summarize new concepts of early and late T cell plasticity and the cytokine network that …
EAE was also very useful to refute the idea that IFN-γ producing T helper type 1 (Th1) cells were the sole players within the pathoge …
18F-FDG PET detects inflammatory infiltrates in spinal cord experimental autoimmune encephalomyelitis lesions.
Buck D, Förschler A, Lapa C, Schuster T, Vollmar P, Korn T, Nessler S, Stadelmann C, Drzezga A, Buck AK, Wester HJ, Zimmer C, Krause BJ, Hemmer B. Buck D, et al. J Nucl Med. 2012 Aug;53(8):1269-76. doi: 10.2967/jnumed.111.102608. Epub 2012 Jun 27. J Nucl Med. 2012. PMID: 22738927
Interaction with antigen-specific T cells regulates expression of the lactate transporter MCT1 in primary rat astrocytes: specific link between immunity and homeostasis.
Korn T, Magnus T, Jung S. Korn T, et al. Glia. 2005 Jan 1;49(1):73-83. doi: 10.1002/glia.20101. Glia. 2005. PMID: 15390096
Resting T cells did not induce a relevant upregulation of MCT1 in astrocytes. However, resting T cells stimulated the expression of MCT1 when anti-MHC class II antibodies, but not when anti-MHC class I antibodies, were added to the co-culture. Therefore, even in the …
Resting T cells did not induce a relevant upregulation of MCT1 in astrocytes. However, resting T cells stimulated the expressi …
Lipooligosaccharide of Campylobacter jejuni prevents myelin-specific enteral tolerance to autoimmune neuritis--a potential mechanism in Guillain-Barre syndrome?
Jung S, Zimmer S, Lüneberg E, Frosch M, Karch H, Korn T, Toyka KV. Jung S, et al. Neurosci Lett. 2005 Jun 10-17;381(1-2):175-8. doi: 10.1016/j.neulet.2005.02.028. Epub 2005 Feb 25. Neurosci Lett. 2005. PMID: 15882812
Additional pathomechanisms, like disturbance of natural T cell immunoregulation by C. jejuni, have not been evaluated so far. In experimental autoimmune neuritis (EAN), a T lymphocyte-mediated animal model of human GBS, tolerance to myelin-derived autoantigens can b …
Additional pathomechanisms, like disturbance of natural T cell immunoregulation by C. jejuni, have not been evaluated so far. In expe …
Microglial expression of the B7 family member B7 homolog 1 confers strong immune inhibition: implications for immune responses and autoimmunity in the CNS.
Magnus T, Schreiner B, Korn T, Jack C, Guo H, Antel J, Ifergan I, Chen L, Bischof F, Bar-Or A, Wiendl H. Magnus T, et al. J Neurosci. 2005 Mar 9;25(10):2537-46. doi: 10.1523/JNEUROSCI.4794-04.2005. J Neurosci. 2005. PMID: 15758163 Free PMC article.
Coculture experiments of major histocompatibility complex class II-positive antigen-presenting cells (APC) with syngeneic T cells in the presence of antigen demonstrated the functional consequences of B7-H1 expression on T-cell activation. ...Expression was predomin …
Coculture experiments of major histocompatibility complex class II-positive antigen-presenting cells (APC) with syngeneic T cells in …
190 results
Jump to page
Feedback