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Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function.
Xiao S, Najafian N, Reddy J, Albin M, Zhu C, Jensen E, Imitola J, Korn T, Anderson AC, Zhang Z, Gutierrez C, Moll T, Sobel RA, Umetsu DT, Yagita H, Akiba H, Strom T, Sayegh MH, DeKruyff RH, Khoury SJ, Kuchroo VK. Xiao S, et al. Among authors: korn t. J Exp Med. 2007 Jul 9;204(7):1691-702. doi: 10.1084/jem.20062498. Epub 2007 Jul 2. J Exp Med. 2007. PMID: 17606630 Free PMC article.
Th17: the third member of the effector T cell trilogy.
Bettelli E, Korn T, Kuchroo VK. Bettelli E, et al. Among authors: korn t. Curr Opin Immunol. 2007 Dec;19(6):652-7. doi: 10.1016/j.coi.2007.07.020. Epub 2007 Sep 4. Curr Opin Immunol. 2007. PMID: 17766098 Free PMC article. Review.
Th17 cells: effector T cells with inflammatory properties.
Korn T, Oukka M, Kuchroo V, Bettelli E. Korn T, et al. Semin Immunol. 2007 Dec;19(6):362-71. doi: 10.1016/j.smim.2007.10.007. Epub 2007 Nov 26. Semin Immunol. 2007. PMID: 18035554 Free PMC article. Review.
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