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SWI/SNF-deficiency defines highly aggressive undifferentiated endometrial carcinoma.
Tessier-Cloutier B, Coatham M, Carey M, Nelson GS, Hamilton S, Lum A, Soslow RA, Stewart CJ, Postovit LM, Köbel M, Lee CH. Tessier-Cloutier B, et al. J Pathol Clin Res. 2020 Oct 30. doi: 10.1002/cjp2.188. Online ahead of print. J Pathol Clin Res. 2020. PMID: 33125840
Comparison of ambulatory central hemodynamics and arterial stiffness in patients with diabetic and non-diabetic CKD.
Loutradis C, Schoina M, Dimitroulas T, Doumas M, Garyfallos A, Karagiannis A, Papagianni A, Sarafidis P. Loutradis C, et al. J Clin Hypertens (Greenwich). 2020 Oct 30. doi: 10.1111/jch.14089. Online ahead of print. J Clin Hypertens (Greenwich). 2020. PMID: 33125832
During day- and nighttime periods, cSBP and cPP levels were higher in diabetics compared to non-diabetics. 24-h PWV (10.101.62 vs. 9.611.80m/s, P=.165) was numerically higher in patients with DM, but no between-group differences were noted in augmentation pressure and inde …
During day- and nighttime periods, cSBP and cPP levels were higher in diabetics compared to non-diabetics. 24-h PWV (10.101.62 vs. 9.611.80m …
Structural Basis of Cav1.1 Modulation by Dihydropyridine Compounds.
Yan N, Gao S. Yan N, et al. Angew Chem Int Ed Engl. 2020 Oct 30. doi: 10.1002/anie.202011793. Online ahead of print. Angew Chem Int Ed Engl. 2020. PMID: 33125829
Here, we report five cryo-EM structures of nanodisc-embedded Ca v 1.1 in the presence of the bestselling drug amlodipine, a DHP antagonist ( R )-(+)-Bay K8644, and a titration of its agonistic enantiomer ( S )-(-)-Bay K8644 at resolutions of 2.9-3.4A. ...All structures wit …
Here, we report five cryo-EM structures of nanodisc-embedded Ca v 1.1 in the presence of the bestselling drug amlodipine, a DHP antagonist ( …
Preliminary data on the potential for unintentional anti-doping rule violations by permitted CBD use.
Mareck U, Fusshöller G, Geyer H, Huestis MA, Scheiff AB, Thevis M. Mareck U, et al. Drug Test Anal. 2020 Oct 30. doi: 10.1002/dta.2959. Online ahead of print. Drug Test Anal. 2020. PMID: 33125823
All other (minor) cannabinoids are reported as AAF when identified, except for CBD that has been explicitly excluded from the class of cannabinoids on WADA's Prohibited List since 2018. ...
All other (minor) cannabinoids are reported as AAF when identified, except for CBD that has been explicitly excluded from the class of canna …
Prediction and measurement of diuretic responsiveness after oral administration of furosemide to healthy dogs and dogs with congestive heart failure.
Loughran KA, Larouche-Lebel É, Huh T, Testani JM, Rao VS, Oyama MA. Loughran KA, et al. J Vet Intern Med. 2020 Oct 30. doi: 10.1111/jvim.15952. Online ahead of print. J Vet Intern Med. 2020. PMID: 33125814
RESULTS: Predicted uNa output at 180 minutes (r(s) =0.763, [95% confidence interval [CI], 0.375-0.923], P =.002) and 270 minutes (r =0.816, [95% CI, 0.503-0.940], P<.001) was highly correlated to 7-hour uNa output. ...
RESULTS: Predicted uNa output at 180 minutes (r(s) =0.763, [95% confidence interval [CI], 0.375-0.923], P =.002) and 270 minutes (r = …
Hydrocephalus Complicating Intrathecal Antisense Oligonucleotide Therapy for Huntington's Disease.
Stoker TB, Andresen KER, Barker RA. Stoker TB, et al. Mov Disord. 2020 Oct 30. doi: 10.1002/mds.28359. Online ahead of print. Mov Disord. 2020. PMID: 33125799 No abstract available.
Reversibly photo-modulating mechanical stiffness and toughness of bioengineered protein fibers.
Liu K, Sun J, Ma C, Maity S, Wang F, Zhou Y, Portale G, Göstl R, Roos WH, Zhang H, Herrmann A. Liu K, et al. Angew Chem Int Ed Engl. 2020 Oct 30. doi: 10.1002/anie.202012848. Online ahead of print. Angew Chem Int Ed Engl. 2020. PMID: 33125796
Specifically, the photo-induced rearrangement into the Z-form of Azo possibly strengthened cation-piinteractions within the fiber material resulting in around twofold increase in the fiber's mechanical performance. ...
Specifically, the photo-induced rearrangement into the Z-form of Azo possibly strengthened cation-piinteractions within the fiber material r …
C/EBPα/miR-7 controls CD4+ T cell activation and function and orchestrates experimental autoimmune hepatitis in mice.
Zhao J, Chu F, Xu H, Guo M, Shan, Zheng W, Tao Y, Zhou Y, Hu Y, Chen C, Ren T, Xu L. Zhao J, et al. Hepatology. 2020 Oct 30. doi: 10.1002/hep.31607. Online ahead of print. Hepatology. 2020. PMID: 33125780
Youth with Disabilities are More Likely than their Peers to Engage in Hazardous Child Labour.
Emerson E, Llewellyn G. Emerson E, et al. Child Care Health Dev. 2020 Oct 30. doi: 10.1111/cch.12820. Online ahead of print. Child Care Health Dev. 2020. PMID: 33125768
METHODS: Secondary analysis of data collected in UNICEF's Multiple Indicator Cluster Surveys. RESULTS: Overall children and youth with disability were not at significantly greater risk of exposure than children without disability to child labour when demographic and contex …
METHODS: Secondary analysis of data collected in UNICEF's Multiple Indicator Cluster Surveys. RESULTS: Overall children and youth wit …
The Role of An Academic Emergency Department in Advancing Equity and Justice.
Landry AM, Brown I, Blomkalns AL, Wolfe RE. Landry AM, et al. Acad Emerg Med. 2020 Oct 30. doi: 10.1111/acem.14164. Online ahead of print. Acad Emerg Med. 2020. PMID: 33125762
The social response raised equity and justice awareness, kickstarting one of the largest movements in U.S. history. A national dialogue on systemic racism as a public health concern has reemerged. ...
The social response raised equity and justice awareness, kickstarting one of the largest movements in U.S. history. A national dialog …
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