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SF3B1 haploinsufficiency leads to formation of ring sideroblasts in myelodysplastic syndromes.
Visconte V, Rogers HJ, Singh J, Barnard J, Bupathi M, Traina F, McMahon J, Makishima H, Szpurka H, Jankowska A, Jerez A, Sekeres MA, Saunthararajah Y, Advani AS, Copelan E, Koseki H, Isono K, Padgett RA, Osman S, Koide K, O'Keefe C, Maciejewski JP, Tiu RV. Visconte V, et al. Among authors: koseki h. Blood. 2012 Oct 18;120(16):3173-86. doi: 10.1182/blood-2012-05-430876. Epub 2012 Jul 23. Blood. 2012. PMID: 22826563 Free PMC article.
Nuclear inhibitor of protein phosphatase-1 (NIPP1) directs protein phosphatase-1 (PP1) to dephosphorylate the U2 small nuclear ribonucleoprotein particle (snRNP) component, spliceosome-associated protein 155 (Sap155).
Tanuma N, Kim SE, Beullens M, Tsubaki Y, Mitsuhashi S, Nomura M, Kawamura T, Isono K, Koseki H, Sato M, Bollen M, Kikuchi K, Shima H. Tanuma N, et al. Among authors: koseki h. J Biol Chem. 2008 Dec 19;283(51):35805-14. doi: 10.1074/jbc.M805468200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842582 Free article.
Splicing factor 3b subunit 1 (Sf3b1) haploinsufficient mice display features of low risk Myelodysplastic syndromes with ring sideroblasts.
Visconte V, Tabarroki A, Zhang L, Parker Y, Hasrouni E, Mahfouz R, Isono K, Koseki H, Sekeres MA, Saunthararajah Y, Barnard J, Lindner D, Rogers HJ, Tiu RV. Visconte V, et al. Among authors: koseki h. J Hematol Oncol. 2014 Dec 7;7:89. doi: 10.1186/s13045-014-0089-x. J Hematol Oncol. 2014. PMID: 25481243 Free PMC article.
Bcor insufficiency promotes initiation and progression of myelodysplastic syndrome.
Tara S, Isshiki Y, Nakajima-Takagi Y, Oshima M, Aoyama K, Tanaka T, Shinoda D, Koide S, Saraya A, Miyagi S, Manabe I, Matsui H, Koseki H, Bardwell VJ, Iwama A. Tara S, et al. Among authors: koseki h. Blood. 2018 Dec 6;132(23):2470-2483. doi: 10.1182/blood-2018-01-827964. Epub 2018 Sep 18. Blood. 2018. PMID: 30228234 Free PMC article.
550 results