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PIM kinases: From survival factors to regulators of cell motility.
Santio NM, Koskinen PJ. Santio NM, et al. Among authors: koskinen pj. Int J Biochem Cell Biol. 2017 Dec;93:74-85. doi: 10.1016/j.biocel.2017.10.016. Epub 2017 Nov 3. Int J Biochem Cell Biol. 2017. PMID: 29108877 Review.
Myc amplification: regulation of myc function.
Koskinen PJ, Mäkelä TP, Västrik I, Alitalo K. Koskinen PJ, et al. Clin Chim Acta. 1993 Jul 30;217(1):57-62. doi: 10.1016/0009-8981(93)90237-x. Clin Chim Acta. 1993. PMID: 8222283 Review.
Role of myc amplification and overexpression in cell growth, differentiation and death.
Koskinen PJ, Alitalo K. Koskinen PJ, et al. Semin Cancer Biol. 1993 Feb;4(1):3-12. Semin Cancer Biol. 1993. PMID: 8448376 Review.
Pim-1 kinase and p100 cooperate to enhance c-Myb activity.
Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB, Eisenman RN, Ness SA. Leverson JD, et al. Among authors: koskinen pj. Mol Cell. 1998 Oct;2(4):417-25. doi: 10.1016/s1097-2765(00)80141-0. Mol Cell. 1998. PMID: 9809063
Interferon-alpha activates multiple STAT proteins and upregulates proliferation-associated IL-2Ralpha, c-myc, and pim-1 genes in human T cells.
Matikainen S, Sareneva T, Ronni T, Lehtonen A, Koskinen PJ, Julkunen I. Matikainen S, et al. Among authors: koskinen pj. Blood. 1999 Mar 15;93(6):1980-91. Blood. 1999. PMID: 10068671
The PIM-1 serine kinase prolongs survival and inhibits apoptosis-related mitochondrial dysfunction in part through a bcl-2-dependent pathway.
Lilly M, Sandholm J, Cooper JJ, Koskinen PJ, Kraft A. Lilly M, et al. Among authors: koskinen pj. Oncogene. 1999 Jul 8;18(27):4022-31. doi: 10.1038/sj.onc.1202741. Oncogene. 1999. PMID: 10435626
Developmental expression of pim kinases suggests functions also outside of the hematopoietic system.
Eichmann A, Yuan L, Bréant C, Alitalo K, Koskinen PJ. Eichmann A, et al. Among authors: koskinen pj. Oncogene. 2000 Feb 24;19(9):1215-24. doi: 10.1038/sj.onc.1203355. Oncogene. 2000. PMID: 10713710
Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase.
Rainio EM, Sandholm J, Koskinen PJ. Rainio EM, et al. Among authors: koskinen pj. J Immunol. 2002 Feb 15;168(4):1524-7. doi: 10.4049/jimmunol.168.4.1524. J Immunol. 2002. PMID: 11823475
The PIM-2 kinase phosphorylates BAD on serine 112 and reverses BAD-induced cell death.
Yan B, Zemskova M, Holder S, Chin V, Kraft A, Koskinen PJ, Lilly M. Yan B, et al. Among authors: koskinen pj. J Biol Chem. 2003 Nov 14;278(46):45358-67. doi: 10.1074/jbc.M307933200. Epub 2003 Sep 3. J Biol Chem. 2003. PMID: 12954615
Attenuation of androgen receptor-dependent transcription by the serine/threonine kinase Pim-1.
Thompson J, Peltola KJ, Koskinen PJ, Jänne OA, Palvimo JJ. Thompson J, et al. Among authors: koskinen pj. Lab Invest. 2003 Sep;83(9):1301-9. doi: 10.1097/01.lab.0000087585.03162.a3. Lab Invest. 2003. PMID: 13679438
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