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Functional characterization of a series of mutant G protein alphaq subunits displaying promiscuous receptor coupling properties.
Kostenis E, Zeng FY, Wess J. Kostenis E, et al. J Biol Chem. 1998 Jul 10;273(28):17886-92. doi: 10.1074/jbc.273.28.17886. J Biol Chem. 1998. PMID: 9651394
We recently showed that an alphaq deletion mutant lacking these six amino acids (in contrast to wild type alphaq) was able to couple to several different Gs- and Gi/o-coupled receptors, apparently due to promiscuous receptor/G protein coupling (Kostenis, E., Degtyar …
We recently showed that an alphaq deletion mutant lacking these six amino acids (in contrast to wild type alphaq) was able to couple to seve …
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