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Developmental biology and tissue engineering.
Marga F, Neagu A, Kosztin I, Forgacs G. Marga F, et al. Birth Defects Res C Embryo Today. 2007 Dec;81(4):320-8. doi: 10.1002/bdrc.20109. Birth Defects Res C Embryo Today. 2007. PMID: 18228266 Review.
Tissue engineering (TE) aims at reproducing morphogenesis in the laboratory, i.e., in vitro, to fabricate replacement organs for regenerative medicine. ...
Tissue engineering (TE) aims at reproducing morphogenesis in the laboratory, i.e., in vitro, to fabricate replacement organs for rege …
Post-deposition bioink self-assembly: a quantitative study.
Shafiee A, McCune M, Forgacs G, Kosztin I. Shafiee A, et al. Among authors: kosztin i. Biofabrication. 2015 Nov 5;7(4):045005. doi: 10.1088/1758-5090/7/4/045005. Biofabrication. 2015. PMID: 26538193
Kinetic Monte Carlo and cellular particle dynamics simulations of multicellular systems.
Flenner E, Janosi L, Barz B, Neagu A, Forgacs G, Kosztin I. Flenner E, et al. Among authors: kosztin i. Phys Rev E Stat Nonlin Soft Matter Phys. 2012 Mar;85(3 Pt 1):031907. doi: 10.1103/PhysRevE.85.031907. Epub 2012 Mar 8. Phys Rev E Stat Nonlin Soft Matter Phys. 2012. PMID: 22587123
Computational modeling of epithelial-mesenchymal transformations.
Neagu A, Mironov V, Kosztin I, Barz B, Neagu M, Moreno-Rodriguez RA, Markwald RR, Forgacs G. Neagu A, et al. Biosystems. 2010 Apr;100(1):23-30. doi: 10.1016/j.biosystems.2009.12.004. Epub 2009 Dec 31. Biosystems. 2010. PMID: 20005917 Free PMC article.
MUFOLD: A new solution for protein 3D structure prediction.
Zhang J, Wang Q, Barz B, He Z, Kosztin I, Shang Y, Xu D. Zhang J, et al. Proteins. 2010 Apr;78(5):1137-52. doi: 10.1002/prot.22634. Proteins. 2010. PMID: 19927325 Free PMC article.
Subdiffusion and lateral diffusion coefficient of lipid atoms and molecules in phospholipid bilayers.
Flenner E, Das J, Rheinstädter MC, Kosztin I. Flenner E, et al. Phys Rev E Stat Nonlin Soft Matter Phys. 2009 Jan;79(1 Pt 1):011907. doi: 10.1103/PhysRevE.79.011907. Epub 2009 Jan 14. Phys Rev E Stat Nonlin Soft Matter Phys. 2009. PMID: 19257069
From the analysis of a 0.1 micros MD trajectory, we find that the time evolution of the mean-square displacement, <[deltar(t)]2>, of lipid atoms and molecules exhibits three well-separated dynamical regions: (i) ballistic, with <[deltar(t)]2> approximately t2 f …
From the analysis of a 0.1 micros MD trajectory, we find that the time evolution of the mean-square displacement, <[deltar(t)]2>, of l …
Motional coherence in fluid phospholipid membranes.
Rheinstädter MC, Das J, Flenner EJ, Brüning B, Seydel T, Kosztin I. Rheinstädter MC, et al. Phys Rev Lett. 2008 Dec 12;101(24):248106. doi: 10.1103/PhysRevLett.101.248106. Epub 2008 Dec 12. Phys Rev Lett. 2008. PMID: 19113677
Relating cell and tissue mechanics: implications and applications.
Jakab K, Damon B, Marga F, Doaga O, Mironov V, Kosztin I, Markwald R, Forgacs G. Jakab K, et al. Dev Dyn. 2008 Sep;237(9):2438-49. doi: 10.1002/dvdy.21684. Dev Dyn. 2008. PMID: 18729216
Membrane curvature and surface area per lipid affect the conformation and oligomeric state of HIV-1 fusion peptide: a combined FTIR and MD simulation study.
Barz B, Wong TC, Kosztin I. Barz B, et al. Biochim Biophys Acta. 2008 Apr;1778(4):945-53. doi: 10.1016/j.bbamem.2007.11.014. Epub 2007 Dec 14. Biochim Biophys Acta. 2008. PMID: 18177732
Relating biophysical properties across scales.
Flenner E, Marga F, Neagu A, Kosztin I, Forgacs G. Flenner E, et al. Curr Top Dev Biol. 2008;81:461-83. doi: 10.1016/S0070-2153(07)81016-7. Curr Top Dev Biol. 2008. PMID: 18023738 Review.
It is this coordinated interplay between genetic and generic (i.e., physical and chemical) processes that constitutes the modern understanding of early morphogenesis. ...
It is this coordinated interplay between genetic and generic (i.e., physical and chemical) processes that constitutes the modern unde …
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