Kotaja N - Search Results

1

The lack of HSD17B3 in male mice results in disturbed Leydig cell maturation and endocrine imbalance akin to humans with HSD17B3 deficiency.

Sipilä P, Junnila A, Hakkarainen J, Huhtaniemi R, Mairinoja L, Zhang FP, Strauss L, Ohlsson C, Kotaja N, Huhtaniemi I, Poutanen M. Sipilä P, et al. Among authors: kotaja n. FASEB J. 2020 May;34(5):6111-6128. doi: 10.1096/fj.201902384R. Epub 2020 Mar 19. FASEB J. 2020. PMID: 32190925

2

Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells.

Rotgers E, Rivero-Müller A, Nurmio M, Parvinen M, Guillou F, Huhtaniemi I, Kotaja N, Bourguiba-Hachemi S, Toppari J. Rotgers E, et al. Among authors: kotaja n. Cell Death Dis. 2014 Jun 5;5(6):e1274. doi: 10.1038/cddis.2014.232. Cell Death Dis. 2014. PMID: 24901045 Free PMC article.

3

FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules.

Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang FP, Vihinen H, Jokitalo E, Sironen A, Toppari J, Kotaja N. Da Ros M, et al. Among authors: kotaja n. Autophagy. 2017 Feb;13(2):302-321. doi: 10.1080/15548627.2016.1261319. Epub 2016 Dec 8. Autophagy. 2017. PMID: 27929729 Free PMC article.

4

SPEF2 functions in microtubule-mediated transport in elongating spermatids to ensure proper male germ cell differentiation.

Lehti MS, Zhang FP, Kotaja N, Sironen A. Lehti MS, et al. Among authors: kotaja n. Development. 2017 Jul 15;144(14):2683-2693. doi: 10.1242/dev.152108. Epub 2017 Jun 15. Development. 2017. PMID: 28619825

5

Hydroxysteroid (17β) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility.

Hakkarainen J, Zhang FP, Jokela H, Mayerhofer A, Behr R, Cisneros-Montalvo S, Nurmio M, Toppari J, Ohlsson C, Kotaja N, Sipilä P, Poutanen M. Hakkarainen J, et al. Among authors: kotaja n. FASEB J. 2018 Jun;32(6):3229-3241. doi: 10.1096/fj.201700921R. Epub 2018 Jan 24. FASEB J. 2018. PMID: 29401623

., Cisneros-Montalvo, S., Nurmio, M., Toppari, J., Ohlsson, C., Kotaja, N., Sipila, P., Poutanen, M. Hydroxysteroid (17beta) dehydrogenase 1 expressed by Sertoli cells contributes to steroid synthesis and is required for male fertility....

., Cisneros-Montalvo, S., Nurmio, M., Toppari, J., Ohlsson, C., Kotaja, N., Sipila, P., Poutanen, M. Hydroxysteroid (17beta) d …

6

Lack of androgen receptor SUMOylation results in male infertility due to epididymal dysfunction.

Zhang FP, Malinen M, Mehmood A, Lehtiniemi T, Jääskeläinen T, Niskanen EA, Korhonen H, Laiho A, Elo LL, Ohlsson C, Kotaja N, Poutanen M, Sipilä P, Palvimo JJ. Zhang FP, et al. Among authors: kotaja n. Nat Commun. 2019 Feb 15;10(1):777. doi: 10.1038/s41467-019-08730-z. Nat Commun. 2019. PMID: 30770815 Free PMC article.

7

SMG6 localizes to the chromatoid body and shapes the male germ cell transcriptome to drive spermatogenesis.

Lehtiniemi T, Bourgery M, Ma L, Ahmedani A, Mäkelä M, Asteljoki J, Olotu O, Laasanen S, Zhang FP, Tan K, Chousal JN, Burow D, Koskinen S, Laiho A, Elo LL, Chalmel F, Wilkinson MF, Kotaja N. Lehtiniemi T, et al. Among authors: kotaja n. Nucleic Acids Res. 2022 Nov 11;50(20):11470-11491. doi: 10.1093/nar/gkac900. Nucleic Acids Res. 2022. PMID: 36259644 Free PMC article.

8

Inhibition of androgen receptor (AR) function by the reproductive orphan nuclear receptor DAX-1.

Holter E, Kotaja N, Mäkela S, Strauss L, Kietz S, Jänne OA, Gustafsson JA, Palvimo JJ, Treuter E. Holter E, et al. Among authors: kotaja n. Mol Endocrinol. 2002 Mar;16(3):515-28. doi: 10.1210/mend.16.3.0804. Mol Endocrinol. 2002. PMID: 11875111

9

Dicer is required for haploid male germ cell differentiation in mice.

Korhonen HM, Meikar O, Yadav RP, Papaioannou MD, Romero Y, Da Ros M, Herrera PL, Toppari J, Nef S, Kotaja N. Korhonen HM, et al. Among authors: kotaja n. PLoS One. 2011;6(9):e24821. doi: 10.1371/journal.pone.0024821. Epub 2011 Sep 16. PLoS One. 2011. PMID: 21949761 Free PMC article.

10

Transcription Factor USF1 Is Required for Maintenance of Germline Stem Cells in Male Mice.

Faisal I, Cisneros-Montalvo S, Hamer G, Tuominen MM, Laurila PP, Tumiati M, Jauhiainen M, Kotaja N, Toppari J, Mäkelä JA, Kauppi L. Faisal I, et al. Among authors: kotaja n. Endocrinology. 2019 May 1;160(5):1119-1136. doi: 10.1210/en.2018-01088. Endocrinology. 2019. PMID: 30759202 Free article.

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