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Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressing angiogenesis.
Tawaramoto K, Kotani K, Hashiramoto M, Kanda Y, Nagare T, Sakaue H, Ogawa W, Emoto N, Yanagisawa M, Noda T, Kasuga M, Kaku K. Tawaramoto K, et al. Among authors: kotani k. Mol Endocrinol. 2012 Jan;26(1):95-109. doi: 10.1210/me.2010-0412. Epub 2011 Nov 22. Mol Endocrinol. 2012. PMID: 22108800 Free PMC article.
Muscle-specific overexpression of heparin-binding epidermal growth factor-like growth factor increases peripheral glucose disposal and insulin sensitivity.
Fukatsu Y, Noguchi T, Hosooka T, Ogura T, Kotani K, Abe T, Shibakusa T, Inoue K, Sakai M, Tobimatsu K, Inagaki K, Yoshioka T, Matsuo M, Nakae J, Matsuki Y, Hiramatsu R, Kaku K, Okamura H, Fushiki T, Kasuga M. Fukatsu Y, et al. Among authors: kotani k. Endocrinology. 2009 Jun;150(6):2683-91. doi: 10.1210/en.2008-1647. Epub 2009 Mar 5. Endocrinology. 2009. PMID: 19264873
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