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A nonfunctioning single nucleotide polymorphism in olfactory receptor gene family is associated with the forced expiratory volume in the first second/the forced vital capacity values of pulmonary function test in a Japanese population.
Takabatake N, Toriyama S, Takeishi Y, Shibata Y, Konta T, Inoue S, Abe S, Igarashi A, Tokairin Y, Ishii M, Koyano S, Emi M, Kato T, Kawata S, Kubota I. Takabatake N, et al. Among authors: koyano s. Biochem Biophys Res Commun. 2007 Dec 21;364(3):662-7. doi: 10.1016/j.bbrc.2007.10.068. Epub 2007 Oct 22. Biochem Biophys Res Commun. 2007. PMID: 17964544
Genetic association between aldehyde dehydrogenase 2 (ALDH2) variation and high-density lipoprotein cholesterol (HDL-C) among non-drinkers in two large population samples in Japan.
Wada M, Daimon M, Emi M, Iijima H, Sato H, Koyano S, Tajima K, Kawanami T, Kurita K, Hunt SC, Hopkins PN, Kubota I, Kawata S, Kato T. Wada M, et al. Among authors: koyano s. J Atheroscler Thromb. 2008 Aug;15(4):179-84. doi: 10.5551/jat.e542. J Atheroscler Thromb. 2008. PMID: 18776700 Free article.
Functional characterization of four naturally occurring variants of human pregnane X receptor (PXR): one variant causes dramatic loss of both DNA binding activity and the transactivation of the CYP3A4 promoter/enhancer region.
Koyano S, Kurose K, Saito Y, Ozawa S, Hasegawa R, Komamura K, Ueno K, Kamakura S, Kitakaze M, Nakajima T, Matsumoto K, Akasawa A, Saito H, Sawada J. Koyano S, et al. Drug Metab Dispos. 2004 Jan;32(1):149-54. doi: 10.1124/dmd.32.1.149. Drug Metab Dispos. 2004. PMID: 14709632
Genetic variations of the AHR gene encoding aryl hydrocarbon receptor in a Japanese population.
Fukushima-Uesaka H, Sai K, Maekawa K, Koyano S, Kaniwa N, Ozawa S, Kawamoto M, Kamatani N, Komamura K, Kamakura S, Kitakaze M, Tomoike H, Ueno K, Minami H, Ohtsu A, Shirao K, Yoshida T, Saijo N, Saito Y, Sawada J. Fukushima-Uesaka H, et al. Among authors: koyano s. Drug Metab Pharmacokinet. 2004 Aug;19(4):320-6. doi: 10.2133/dmpk.19.320. Drug Metab Pharmacokinet. 2004. PMID: 15499202 Free article.
Eleven novel single nucleotide polymorphisms in the NR1I2 (PXR) gene, four of which induce non-synonymous amino acid alterations.
Koyano S, Kurose K, Ozawa S, Saeki M, Nakajima Y, Hasegawa R, Komamura K, Ueno K, Kamakura S, Nakajima T, Saito H, Kimura H, Goto Y, Saitoh O, Katoh M, Ohnuma T, Kawai M, Sugai K, Ohtsuki T, Suzuki C, Minami N, Saito Y, Sawada J. Koyano S, et al. Drug Metab Pharmacokinet. 2002;17(6):561-5. doi: 10.2133/dmpk.17.561. Drug Metab Pharmacokinet. 2002. PMID: 15618712 Free article.
152 results