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Galpha 12 activates Rho GTPase through tyrosine-phosphorylated leukemia-associated RhoGEF.
Suzuki N, Nakamura S, Mano H, Kozasa T. Suzuki N, et al. Among authors: kozasa t. Proc Natl Acad Sci U S A. 2003 Jan 21;100(2):733-8. doi: 10.1073/pnas.0234057100. Epub 2003 Jan 6. Proc Natl Acad Sci U S A. 2003. PMID: 12515866 Free PMC article.
Recently, we identified p115RhoGEF, one of the guanine nucleotide exchange factors (GEFs) for Rho, as a direct link between Galpha13 and Rho [Kozasa, T., et al. (1998) Science 280, 2109-2111; Hart, M. J., et al. (1998) Science 280, 2112-2114]. ...
Recently, we identified p115RhoGEF, one of the guanine nucleotide exchange factors (GEFs) for Rho, as a direct link between Galpha13 and Rho …
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