Kozikowski AP - Search Results

1

3-(Hydroxymethyl)-bearing phosphatidylinositol ether lipid analogues and carbonate surrogates block PI3-K, Akt, and cancer cell growth.

Hu Y, Qiao L, Wang S, Rong SB, Meuillet EJ, Berggren M, Gallegos A, Powis G, Kozikowski AP. Hu Y, et al. Among authors: kozikowski ap. J Med Chem. 2000 Aug 10;43(16):3045-51. doi: 10.1021/jm000117y. J Med Chem. 2000. PMID: 10956212

2

Structural basis of RasGRP binding to high-affinity PKC ligands.

Rong SB, Enyedy IJ, Qiao L, Zhao L, Ma D, Pearce LL, Lorenzo PS, Stone JC, Blumberg PM, Wang S, Kozikowski AP. Rong SB, et al. Among authors: kozikowski ap. J Med Chem. 2002 Feb 14;45(4):853-60. doi: 10.1021/jm010422z. J Med Chem. 2002. PMID: 11831896

3

Molecular modeling of the interactions of glutamate carboxypeptidase II with its potent NAAG-based inhibitors.

Rong SB, Zhang J, Neale JH, Wroblewski JT, Wang S, Kozikowski AP. Rong SB, et al. Among authors: kozikowski ap. J Med Chem. 2002 Sep 12;45(19):4140-52. doi: 10.1021/jm010561g. J Med Chem. 2002. PMID: 12213057

4

3-Deoxy-D-myo-inositol 1-phosphate, 1-phosphonate, and ether lipid analogues as inhibitors of phosphatidylinositol-3-kinase signaling and cancer cell growth.

Qiao L, Nan F, Kunkel M, Gallegos A, Powis G, Kozikowski AP. Qiao L, et al. Among authors: kozikowski ap. J Med Chem. 1998 Aug 27;41(18):3303-6. doi: 10.1021/jm980254j. J Med Chem. 1998. PMID: 9719581 No abstract available.

5

3-Deoxy-3-substituted-D-myo-inositol imidazolyl ether lipid phosphates and carbonate as inhibitors of the phosphatidylinositol 3-kinase pathway and cancer cell growth.

Hu Y, Meuillet EJ, Berggren M, Powis G, Kozikowski AP. Hu Y, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2001 Jan 22;11(2):173-6. doi: 10.1016/s0960-894x(00)00640-5. Bioorg Med Chem Lett. 2001. PMID: 11206452

6

Molecular modeling studies of the Akt PH domain and its interaction with phosphoinositides.

Rong SB, Hu Y, Enyedy I, Powis G, Meuillet EJ, Wu X, Wang R, Wang S, Kozikowski AP. Rong SB, et al. Among authors: kozikowski ap. J Med Chem. 2001 Mar 15;44(6):898-908. doi: 10.1021/jm000493i. J Med Chem. 2001. PMID: 11300871

7

Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth.

Qiao L, Zhao LY, Rong SB, Wu XW, Wang S, Fujii T, Kazanietz MG, Rauser L, Savage J, Roth BL, Flippen-Anderson J, Kozikowski AP. Qiao L, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2001 Apr 23;11(8):955-9. doi: 10.1016/s0960-894x(01)00097-x. Bioorg Med Chem Lett. 2001. PMID: 11327599

8

Thiophene derivatives: a new series of potent norepinephrine and serotonin reuptake inhibitors.

Zhang A, Zhou G, Rong SB, Johnson KM, Zhang M, Kozikowski AP. Zhang A, et al. Among authors: kozikowski ap. Bioorg Med Chem Lett. 2002 Apr 8;12(7):993-5. doi: 10.1016/s0960-894x(02)00103-8. Bioorg Med Chem Lett. 2002. PMID: 11909701

9

Synthesis and biology of 1D-3-deoxyphosphatidylinositol: a putative antimetabolite of phosphatidylinositol-3-phosphate and an inhibitor of cancer cell colony formation.

Kozikowski AP, Kiddle JJ, Frew T, Berggren M, Powis G. Kozikowski AP, et al. J Med Chem. 1995 Mar 31;38(7):1053-6. doi: 10.1021/jm00007a001. J Med Chem. 1995. PMID: 7707307 No abstract available.

10

Modeling, chemistry, and biology of the benzolactam analogues of indolactam V (ILV). 2. Identification of the binding site of the benzolactams in the CRD2 activator-binding domain of PKCdelta and discovery of an ILV analogue of improved isozyme selectivity.

Kozikowski AP, Wang S, Ma D, Yao J, Ahmad S, Glazer RI, Bogi K, Acs P, Modarres S, Lewin NE, Blumberg PM. Kozikowski AP, et al. J Med Chem. 1997 Apr 25;40(9):1316-26. doi: 10.1021/jm960875h. J Med Chem. 1997. PMID: 9135029

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