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Cancer predisposing BARD1 mutations affect exon skipping and are associated with overexpression of specific BARD1 isoforms.
Ratajska M, Matusiak M, Kuzniacka A, Wasag B, Brozek I, Biernat W, Koczkowska M, Debniak J, Sniadecki M, Kozlowski P, Klonowska K, Pilyugin M, Wydra D, Laurent G, Limon J, Irminger-Finger I. Ratajska M, et al. Among authors: kozlowski p. Oncol Rep. 2015 Nov;34(5):2609-17. doi: 10.3892/or.2015.4235. Epub 2015 Sep 1. Oncol Rep. 2015. PMID: 26329992
Analysis of large mutations in BARD1 in patients with breast and/or ovarian cancer: the Polish population as an example.
Klonowska K, Ratajska M, Czubak K, Kuzniacka A, Brozek I, Koczkowska M, Sniadecki M, Debniak J, Wydra D, Balut M, Stukan M, Zmienko A, Nowakowska B, Irminger-Finger I, Limon J, Kozlowski P. Klonowska K, et al. Among authors: kozlowski p. Sci Rep. 2015 May 21;5:10424. doi: 10.1038/srep10424. Sci Rep. 2015. PMID: 25994375 Free PMC article.
The 30 kb deletion in the APOBEC3 cluster decreases APOBEC3A and APOBEC3B expression and creates a transcriptionally active hybrid gene but does not associate with breast cancer in the European population.
Klonowska K, Kluzniak W, Rusak B, Jakubowska A, Ratajska M, Krawczynska N, Vasilevska D, Czubak K, Wojciechowska M, Cybulski C, Lubinski J, Kozlowski P. Klonowska K, et al. Among authors: kozlowski p. Oncotarget. 2017 Jul 19;8(44):76357-76374. doi: 10.18632/oncotarget.19400. eCollection 2017 Sep 29. Oncotarget. 2017. PMID: 29100317 Free PMC article.
777 results