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Gasdermin D plays a vital role in the generation of neutrophil extracellular traps.
Sollberger G, Choidas A, Burn GL, Habenberger P, Di Lucrezia R, Kordes S, Menninger S, Eickhoff J, Nussbaumer P, Klebl B, Krüger R, Herzig A, Zychlinsky A. Sollberger G, et al. Among authors: kruger r. Sci Immunol. 2018 Aug 24;3(26):eaar6689. doi: 10.1126/sciimmunol.aar6689. Sci Immunol. 2018. PMID: 30143555
β2 integrin mediates hantavirus-induced release of neutrophil extracellular traps.
Raftery MJ, Lalwani P, Krautkrӓmer E, Peters T, Scharffetter-Kochanek K, Krüger R, Hofmann J, Seeger K, Krüger DH, Schönrich G. Raftery MJ, et al. Among authors: kruger r, kruger dh. J Exp Med. 2014 Jun 30;211(7):1485-97. doi: 10.1084/jem.20131092. Epub 2014 Jun 2. J Exp Med. 2014. PMID: 24889201 Free PMC article. Clinical Trial.
Neutrophil extracellular traps drive inflammatory pathogenesis in malaria.
Knackstedt SL, Georgiadou A, Apel F, Abu-Abed U, Moxon CA, Cunnington AJ, Raupach B, Cunningham D, Langhorne J, Krüger R, Barrera V, Harding SP, Berg A, Patel S, Otterdal K, Mordmüller B, Schwarzer E, Brinkmann V, Zychlinsky A, Amulic B. Knackstedt SL, et al. Among authors: kruger r. Sci Immunol. 2019 Oct 18;4(40):eaaw0336. doi: 10.1126/sciimmunol.aaw0336. Sci Immunol. 2019. PMID: 31628160 Free PMC article.
Panton-Valentine leukocidin-induced neutrophil extracellular traps lack antimicrobial activity and are readily induced in patients with recurrent PVL + -Staphylococcus aureus infections.
Jhelum H, Čerina D, Harbort CJ, Lindner A, Hanitsch LG, Leistner R, Schröder JT, von Bernuth H, Stegemann MS, Schürmann M, Zychlinsky A, Krüger R, Marsman G. Jhelum H, et al. Among authors: kruger r. J Leukoc Biol. 2024 Jan 19;115(2):222-234. doi: 10.1093/jleuko/qiad137. J Leukoc Biol. 2024. PMID: 37943843
The GAIN Registry - a New Prospective Study for Patients with Multi-organ Autoimmunity and Autoinflammation.
Staus P, Rusch S, El-Helou S, Müller G, Krausz M, Geisen U, Caballero-Oteyza A, Krüger R, Bakhtiar S, Lee-Kirsch MA, Fasshauer M, Baumann U, Hoyer BF, Farela Neves J, Borte M, Carrabba M, Hauck F, Ehl S, Bader P, von Bernuth H, Atschekzei F, Seppänen MRJ, Warnatz K, Nieters A, Kindle G, Grimbacher B. Staus P, et al. Among authors: kruger r. J Clin Immunol. 2023 Aug;43(6):1289-1301. doi: 10.1007/s10875-023-01472-0. Epub 2023 Apr 21. J Clin Immunol. 2023. PMID: 37084016 Free PMC article.
Infectious and immunologic phenotype of MECP2 duplication syndrome.
Bauer M, Kölsch U, Krüger R, Unterwalder N, Hameister K, Kaiser FM, Vignoli A, Rossi R, Botella MP, Budisteanu M, Rosello M, Orellana C, Tejada MI, Papuc SM, Patat O, Julia S, Touraine R, Gomes T, Wenner K, Xu X, Afenjar A, Toutain A, Philip N, Jezela-Stanek A, Gortner L, Martinez F, Echenne B, Wahn V, Meisel C, Wieczorek D, El-Chehadeh S, Van Esch H, von Bernuth H. Bauer M, et al. Among authors: kruger r. J Clin Immunol. 2015 Feb;35(2):168-81. doi: 10.1007/s10875-015-0129-5. Epub 2015 Feb 27. J Clin Immunol. 2015. PMID: 25721700 Free PMC article.
Gene-Dose Effect of MEFV Gain-of-Function Mutations Determines ex vivo Neutrophil Activation in Familial Mediterranean Fever.
Stoler I, Freytag J, Orak B, Unterwalder N, Henning S, Heim K, von Bernuth H, Krüger R, Winkler S, Eschenhagen P, Seipelt E, Mall MA, Foell D, Kessel C, Wittkowski H, Kallinich T. Stoler I, et al. Among authors: kruger r. Front Immunol. 2020 Jun 11;11:716. doi: 10.3389/fimmu.2020.00716. eCollection 2020. Front Immunol. 2020. PMID: 32655537 Free PMC article.
1,058 results