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Four weeks of treatment with liraglutide reduces insulin dose without loss of glycemic control in type 1 diabetic patients with and without residual beta-cell function.
Kielgast U, Krarup T, Holst JJ, Madsbad S. Kielgast U, et al. Diabetes Care. 2011 Jul;34(7):1463-8. doi: 10.2337/dc11-0096. Epub 2011 May 18. Diabetes Care. 2011. PMID: 21593296 Free PMC article. Clinical Trial.
Glucagon-like peptide receptor agonists and dipeptidyl peptidase-4 inhibitors in the treatment of diabetes: a review of clinical trials.
Madsbad S, Krarup T, Deacon CF, Holst JJ. Madsbad S, et al. Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):491-9. doi: 10.1097/MCO.0b013e328302f414. Curr Opin Clin Nutr Metab Care. 2008. PMID: 18542012 Review.
GLP-1: physiological effects and potential therapeutic applications.
Aaboe K, Krarup T, Madsbad S, Holst JJ. Aaboe K, et al. Diabetes Obes Metab. 2008 Nov;10(11):994-1003. doi: 10.1111/j.1463-1326.2008.00853.x. Epub 2008 Apr 22. Diabetes Obes Metab. 2008. PMID: 18435775 Review.
Liraglutide, a long-acting human glucagon-like peptide-1 analog, given as monotherapy significantly improves glycemic control and lowers body weight without risk of hypoglycemia in patients with type 2 diabetes.
Vilsbøll T, Zdravkovic M, Le-Thi T, Krarup T, Schmitz O, Courrèges JP, Verhoeven R, Bugánová I, Madsbad S. Vilsbøll T, et al. Diabetes Care. 2007 Jun;30(6):1608-10. doi: 10.2337/dc06-2593. Epub 2007 Mar 19. Diabetes Care. 2007. PMID: 17372153 Clinical Trial. No abstract available.
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Knop FK, Vilsbøll T, Højberg PV, Larsen S, Madsbad S, Vølund A, Holst JJ, Krarup T. Knop FK, et al. Diabetes. 2007 Aug;56(8):1951-9. doi: 10.2337/db07-0100. Epub 2007 May 18. Diabetes. 2007. PMID: 17513701
Glucagon-like peptide-2, but not glucose-dependent insulinotropic polypeptide, stimulates glucagon release in patients with type 1 diabetes.
Christensen M, Knop FK, Vilsbøll T, Aaboe K, Holst JJ, Madsbad S, Krarup T. Christensen M, et al. Regul Pept. 2010 Aug 9;163(1-3):96-101. doi: 10.1016/j.regpep.2010.05.004. Epub 2010 May 24. Regul Pept. 2010. PMID: 20580750
KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes.
Aaboe K, Knop FK, Vilsboll T, Vølund A, Simonsen U, Deacon CF, Madsbad S, Holst JJ, Krarup T. Aaboe K, et al. J Clin Endocrinol Metab. 2009 Feb;94(2):603-8. doi: 10.1210/jc.2008-1731. Epub 2008 Dec 2. J Clin Endocrinol Metab. 2009. PMID: 19050053 Clinical Trial.
Glucagon-like peptide-1, glucose homeostasis and diabetes.
Holst JJ, Deacon CF, Vilsbøll T, Krarup T, Madsbad S. Holst JJ, et al. Trends Mol Med. 2008 Apr;14(4):161-8. doi: 10.1016/j.molmed.2008.01.003. Epub 2008 Mar 18. Trends Mol Med. 2008. PMID: 18353723 Review.
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