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Anticancer carrier-linked prodrugs in clinical trials.
Kratz F, Abu Ajaj K, Warnecke A. Kratz F, et al. Expert Opin Investig Drugs. 2007 Jul;16(7):1037-58. doi: 10.1517/13543784.16.7.1037. Expert Opin Investig Drugs. 2007. PMID: 17594188 Review.
A clinical update of using albumin as a drug vehicle - a commentary.
Kratz F. Kratz F. J Control Release. 2014 Sep 28;190:331-6. doi: 10.1016/j.jconrel.2014.03.013. Epub 2014 Mar 15. J Control Release. 2014. PMID: 24637463 Review.
Finding the optimal balance: challenges of improving conventional cancer chemotherapy using suitable combinations with nano-sized drug delivery systems.
Kratz F, Warnecke A. Kratz F, et al. J Control Release. 2012 Dec 10;164(2):221-35. doi: 10.1016/j.jconrel.2012.05.045. Epub 2012 Jun 13. J Control Release. 2012. PMID: 22705248 Review.
Clinical impact of serum proteins on drug delivery.
Kratz F, Elsadek B. Kratz F, et al. J Control Release. 2012 Jul 20;161(2):429-45. doi: 10.1016/j.jconrel.2011.11.028. Epub 2011 Dec 1. J Control Release. 2012. PMID: 22155554 Review.
Development of efficient acid cleavable multifunctional prodrugs derived from dendritic polyglycerol with a poly(ethylene glycol) shell.
Calderón M, Welker P, Licha K, Fichtner I, Graeser R, Haag R, Kratz F. Calderón M, et al. J Control Release. 2011 May 10;151(3):295-301. doi: 10.1016/j.jconrel.2011.01.017. Epub 2011 Jan 21. J Control Release. 2011. PMID: 21256902
A thermally responsive biopolymer conjugated to an acid-sensitive derivative of paclitaxel stabilizes microtubules, arrests cell cycle, and induces apoptosis.
Moktan S, Ryppa C, Kratz F, Raucher D. Moktan S, et al. Invest New Drugs. 2012 Feb;30(1):236-48. doi: 10.1007/s10637-010-9560-x. Epub 2010 Oct 12. Invest New Drugs. 2012. PMID: 20938714
Combination therapy with the albumin-binding prodrug of doxorubicin (INNO-206) and doxorubicin achieves complete remissions and improves tolerability in an ovarian A2780 xenograft model.
Kratz F, Fichtner I, Graeser R. Kratz F, et al. Invest New Drugs. 2012 Aug;30(4):1743-9. doi: 10.1007/s10637-011-9686-5. Epub 2011 May 18. Invest New Drugs. 2012. PMID: 21590366 No abstract available.
Integrin-targeted nano-sized polymeric systems for paclitaxel conjugation: a comparative study.
Eldar-Boock A, Blau R, Ryppa C, Baabur-Cohen H, Many A, Vicent MJ, Kratz F, Sanchis J, Satchi-Fainaro R. Eldar-Boock A, et al. Among authors: kratz f. J Drug Target. 2017 Nov-Dec;25(9-10):829-844. doi: 10.1080/1061186X.2017.1358727. Epub 2017 Aug 8. J Drug Target. 2017. PMID: 28737432
Novel auristatin E-based albumin-binding prodrugs with superior anticancer efficacy in vivo compared to the parent compound.
Pes L, Koester SD, Magnusson JP, Chercheja S, Medda F, Abu Ajaj K, Rognan D, Daum S, Nollmann FI, Garcia Fernandez J, Perez Galan P, Walter HK, Warnecke A, Kratz F. Pes L, et al. Among authors: kratz f. J Control Release. 2019 Feb 28;296:81-92. doi: 10.1016/j.jconrel.2019.01.010. Epub 2019 Jan 11. J Control Release. 2019. PMID: 30639692
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