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Lipid-lowering effects of WAY-121,898, an inhibitor of pancreatic cholesteryl ester hydrolase.
Krause BR, Sliskovic DR, Anderson M, Homan R. Krause BR, et al. Lipids. 1998 May;33(5):489-98. doi: 10.1007/s11745-998-0232-8. Lipids. 1998. PMID: 9625596
The combined effect of inhibiting both ACAT and HMG-CoA reductase may directly induce atherosclerotic lesion regression.
Bocan TM, Krause BR, Rosebury WS, Lu X, Dagle C, Bak Mueller S, Auerbach B, Sliskovic DR. Bocan TM, et al. Among authors: krause br. Atherosclerosis. 2001 Jul;157(1):97-105. doi: 10.1016/s0021-9150(00)00713-9. Atherosclerosis. 2001. PMID: 11427208
The ACAT inhibitor avasimibe reduces macrophages and matrix metalloproteinase expression in atherosclerotic lesions of hypercholesterolemic rabbits.
Bocan TM, Krause BR, Rosebury WS, Mueller SB, Lu X, Dagle C, Major T, Lathia C, Lee H. Bocan TM, et al. Among authors: krause br. Arterioscler Thromb Vasc Biol. 2000 Jan;20(1):70-9. doi: 10.1161/01.atv.20.1.70. Arterioscler Thromb Vasc Biol. 2000. PMID: 10634802
Lack of predictability of classical animal models for hypolipidemic activity: a good time for mice?
Krause BR, Princen HM. Krause BR, et al. Atherosclerosis. 1998 Sep;140(1):15-24. doi: 10.1016/s0021-9150(98)00141-5. Atherosclerosis. 1998. PMID: 9733211 Review.
Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT) as hypocholesterolemic agents: synthesis and structure-activity relationships of novel series of sulfonamides, acylphosphonamides and acylphosphoramidates.
Lee HT, Roark WH, Picard JA, Sliskovic DR, Roth BD, Stanfield RL, Hamelehle KL, Bousley RF, Krause BR. Lee HT, et al. Among authors: krause br. Bioorg Med Chem Lett. 1998 Feb 3;8(3):289-94. doi: 10.1016/s0960-894x(98)00011-0. Bioorg Med Chem Lett. 1998. PMID: 9871672
Inhibitors of acyl-CoA:cholesterol acyltransferase: novel trisubstituted ureas as hypocholesterolemic agents.
Purchase TS, Essenburg AD, Hamelehle KL, Hes MS, Holmes A, Krause BR, Stanfield RL, Trivedi BK. Purchase TS, et al. Among authors: krause br. Bioorg Med Chem. 1997 Apr;5(4):739-47. doi: 10.1016/s0968-0896(97)00019-9. Bioorg Med Chem. 1997. PMID: 9158873
Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.
Haubenwallner S, Essenburg AD, Barnett BC, Pape ME, DeMattos RB, Krause BR, Minton LL, Auerbach BJ, Newton RS, Leff T, et al. Haubenwallner S, et al. Among authors: krause br. J Lipid Res. 1995 Dec;36(12):2541-51. J Lipid Res. 1995. PMID: 8847480
High correlation but lack of agreement between direct high-performance gel chromatography analysis and conventional indirect methods for determining lipoprotein cholesterol.
Krause BR, Schork NJ, Kieft KA, Smith MP, Maciejko JJ. Krause BR, et al. Clin Chem. 1996 Dec;42(12):1996-2001. Clin Chem. 1996. PMID: 8969639
Elevated hepatic apolipoprotein A-I transcription is associated with diet-induced hyperalphalipoproteinemia in rabbits.
Schwab DA, Rea TJ, Hanselman JC, Bisgaier CL, Krause BR, Pape ME. Schwab DA, et al. Among authors: krause br. Life Sci. 2000 Mar 24;66(18):1683-94. doi: 10.1016/s0024-3205(00)00491-4. Life Sci. 2000. PMID: 10809165
alpha-Substituted malonester amides: tools to define the relationship between ACAT inhibition and adrenal toxicity.
Sliskovic DR, Picard JA, O'Brien PM, Liao P, Roark WH, Roth BD, Anderson MA, Mueller SB, Bocan TM, Bousley RF, Hamelehle KL, Homan R, Reindel JF, Stanfield RL, Turluck D, Krause BR. Sliskovic DR, et al. Among authors: krause br. J Med Chem. 1998 Feb 26;41(5):682-90. doi: 10.1021/jm970560h. J Med Chem. 1998. PMID: 9513596
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