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Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
Shou M, Krausz KW, Gonzalez FJ, Gelboin HV. Shou M, et al. Among authors: krausz kw. Arch Biochem Biophys. 1996 Apr 1;328(1):201-7. doi: 10.1006/abbi.1996.0161. Arch Biochem Biophys. 1996. PMID: 8638931
Monoclonal antibodies to cytochromes P450.
Gelboin HV, Shou M, Goldfarb I, Yang TJ, Krausz K. Gelboin HV, et al. Methods Mol Biol. 1998;107:227-37. doi: 10.1385/0-89603-519-0:227. Methods Mol Biol. 1998. PMID: 14577233 No abstract available.
CYP2C subfamily, primarily CYP2C9, catalyses the enantioselective demethylation of the endocrine disruptor pesticide methoxychlor in human liver microsomes: use of inhibitory monoclonal antibodies in P450 identification.
Hu Y, Krausz K, Gelboin HV, Kupfer D. Hu Y, et al. Xenobiotica. 2004 Feb;34(2):117-32. doi: 10.1080/00498250310001644535. Xenobiotica. 2004. PMID: 14985143
Cross-reactivity of thirteen monoclonal antibodies with ten vaccinia cDNA expressed rat, mouse and human cytochrome P450s.
Goldfarb I, Korzekwa K, Krausz KW, Gonzalez F, Gelboin HV. Goldfarb I, et al. Among authors: krausz kw. Biochem Pharmacol. 1993 Sep 1;46(5):787-90. doi: 10.1016/0006-2952(93)90485-f. Biochem Pharmacol. 1993. PMID: 8373431
Monoclonal antibodies specific and inhibitory to human cytochromes P450 2C8, 2C9, and 2C19.
Krausz KW, Goldfarb I, Buters JT, Yang TJ, Gonzalez FJ, Gelboin HV. Krausz KW, et al. Drug Metab Dispos. 2001 Nov;29(11):1410-23. Drug Metab Dispos. 2001. PMID: 11602516
An inhibitory monoclonal antibody to human cytochrome P450 that specifically binds and inhibits P4502C9II, an allelic variant of P4502C9 having a single amino acid change Arg144 Cys.
Krausz KW, Goldfarb I, Yang TJ, Gonzalez FJ, Gelboin HV. Krausz KW, et al. Xenobiotica. 2000 Jun;30(6):619-25. doi: 10.1080/004982500406444. Xenobiotica. 2000. PMID: 10923863
Assessment of specificity of eight chemical inhibitors using cDNA-expressed cytochromes P450.
Sai Y, Dai R, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV, Shou M. Sai Y, et al. Among authors: krausz kw. Xenobiotica. 2000 Apr;30(4):327-43. doi: 10.1080/004982500237541. Xenobiotica. 2000. PMID: 10821163
Use of inhibitory monoclonal antibodies to assess the contribution of cytochromes P450 to human drug metabolism.
Shou M, Lu T, Krausz KW, Sai Y, Yang T, Korzekwa KR, Gonzalez FJ, Gelboin HV. Shou M, et al. Among authors: krausz kw. Eur J Pharmacol. 2000 Apr 14;394(2-3):199-209. doi: 10.1016/s0014-2999(00)00079-0. Eur J Pharmacol. 2000. PMID: 10771285
Inhibitory monoclonal antibodies to human cytochrome P450 enzymes: a new avenue for drug discovery.
Gelboin HV, Krausz KW, Gonzalez FJ, Yang TJ. Gelboin HV, et al. Among authors: krausz kw. Trends Pharmacol Sci. 1999 Nov;20(11):432-8. doi: 10.1016/s0165-6147(99)01382-6. Trends Pharmacol Sci. 1999. PMID: 10542439 Review. No abstract available.
An inhibitory monoclonal antibody to human cytochrome P450 2A6 defines its role in the metabolism of coumarin, 7-ethoxycoumarin and 4-nitroanisole in human liver.
Sai Y, Yang TJ, Krausz KW, Gonzalez FJ, Gelboin HV. Sai Y, et al. Among authors: krausz kw. Pharmacogenetics. 1999 Apr;9(2):229-37. Pharmacogenetics. 1999. PMID: 10376770
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