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71 results
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Molecular requirements for epithelial-mesenchymal transition during tumor progression.
Huber MA, Kraut N, Beug H. Huber MA, et al. Among authors: kraut n. Curr Opin Cell Biol. 2005 Oct;17(5):548-58. doi: 10.1016/j.ceb.2005.08.001. Curr Opin Cell Biol. 2005. PMID: 16098727 Review.
Transcriptional plasticity promotes primary and acquired resistance to BET inhibition.
Rathert P, Roth M, Neumann T, Muerdter F, Roe JS, Muhar M, Deswal S, Cerny-Reiterer S, Peter B, Jude J, Hoffmann T, Boryń ŁM, Axelsson E, Schweifer N, Tontsch-Grunt U, Dow LE, Gianni D, Pearson M, Valent P, Stark A, Kraut N, Vakoc CR, Zuber J. Rathert P, et al. Among authors: kraut n. Nature. 2015 Sep 24;525(7570):543-547. doi: 10.1038/nature14898. Epub 2015 Sep 14. Nature. 2015. PMID: 26367798 Free PMC article.
The small-molecule inhibitor BI 2536 reveals novel insights into mitotic roles of polo-like kinase 1.
Lénárt P, Petronczki M, Steegmaier M, Di Fiore B, Lipp JJ, Hoffmann M, Rettig WJ, Kraut N, Peters JM. Lénárt P, et al. Among authors: kraut n. Curr Biol. 2007 Feb 20;17(4):304-15. doi: 10.1016/j.cub.2006.12.046. Epub 2007 Feb 8. Curr Biol. 2007. PMID: 17291761
Polo-like kinase 1 triggers the initiation of cytokinesis in human cells by promoting recruitment of the RhoGEF Ect2 to the central spindle.
Petronczki M, Glotzer M, Kraut N, Peters JM. Petronczki M, et al. Among authors: kraut n. Dev Cell. 2007 May;12(5):713-25. doi: 10.1016/j.devcel.2007.03.013. Dev Cell. 2007. PMID: 17488623
Characterization of cancer stroma markers: in silico analysis of an mRNA expression database for fibroblast activation protein and endosialin.
Dolznig H, Schweifer N, Puri C, Kraut N, Rettig WJ, Kerjaschki D, Garin-Chesa P. Dolznig H, et al. Among authors: kraut n. Cancer Immun. 2005 Aug 3;5:10. Cancer Immun. 2005. PMID: 16076089
Expression profiling of epithelial plasticity in tumor progression.
Jechlinger M, Grunert S, Tamir IH, Janda E, Lüdemann S, Waerner T, Seither P, Weith A, Beug H, Kraut N. Jechlinger M, et al. Among authors: kraut n. Oncogene. 2003 Oct 16;22(46):7155-69. doi: 10.1038/sj.onc.1206887. Oncogene. 2003. PMID: 14562044
BI 5700, a Selective Chemical Inhibitor of IκB Kinase 2, Specifically Suppresses Epithelial-Mesenchymal Transition and Metastasis in Mouse Models of Tumor Progression.
Huber MA, Maier HJ, Alacakaptan M, Wiedemann E, Braunger J, Boehmelt G, Madwed JB, Young ER, Marshall DR, Pehamberger H, Wirth T, Kraut N, Beug H. Huber MA, et al. Among authors: kraut n. Genes Cancer. 2010 Feb;1(2):101-14. doi: 10.1177/1947601910361749. Genes Cancer. 2010. PMID: 21779445 Free PMC article.
BI 2536, a potent and selective inhibitor of polo-like kinase 1, inhibits tumor growth in vivo.
Steegmaier M, Hoffmann M, Baum A, Lénárt P, Petronczki M, Krssák M, Gürtler U, Garin-Chesa P, Lieb S, Quant J, Grauert M, Adolf GR, Kraut N, Peters JM, Rettig WJ. Steegmaier M, et al. Among authors: kraut n. Curr Biol. 2007 Feb 20;17(4):316-22. doi: 10.1016/j.cub.2006.12.037. Epub 2007 Feb 8. Curr Biol. 2007. PMID: 17291758
Autocrine PDGFR signaling promotes mammary cancer metastasis.
Jechlinger M, Sommer A, Moriggl R, Seither P, Kraut N, Capodiecci P, Donovan M, Cordon-Cardo C, Beug H, Grünert S. Jechlinger M, et al. Among authors: kraut n. J Clin Invest. 2006 Jun;116(6):1561-70. doi: 10.1172/JCI24652. J Clin Invest. 2006. PMID: 16741576 Free PMC article.
NF-kappaB is essential for epithelial-mesenchymal transition and metastasis in a model of breast cancer progression.
Huber MA, Azoitei N, Baumann B, Grünert S, Sommer A, Pehamberger H, Kraut N, Beug H, Wirth T. Huber MA, et al. Among authors: kraut n. J Clin Invest. 2004 Aug;114(4):569-81. doi: 10.1172/JCI21358. J Clin Invest. 2004. PMID: 15314694 Free PMC article.
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