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Thapsigargin activates univalent- and bivalent-cation entry in human neutrophils by a SK&F I3 96365- and Gd3+-sensitive pathway and is a partial secretagogue: involvement of pertussis-toxin-sensitive G-proteins and protein phosphatases 1/2A and 2B in the signal-transduction pathway.
Wenzel-Seifert K, Krautwurst D, Musgrave I, Seifert R. Wenzel-Seifert K, et al. Among authors: krautwurst d. Biochem J. 1996 Mar 1;314 ( Pt 2)(Pt 2):679-86. doi: 10.1042/bj3140679. Biochem J. 1996. PMID: 8670085 Free PMC article.
Formyl peptides and ATP stimulate Ca2+ and Na+ inward currents through non-selective cation channels via G-proteins in dibutyryl cyclic AMP-differentiated HL-60 cells. Involvement of Ca2+ and Na+ in the activation of beta-glucuronidase release and superoxide production.
Krautwurst D, Seifert R, Hescheler J, Schultz G. Krautwurst D, et al. Biochem J. 1992 Dec 15;288 ( Pt 3)(Pt 3):1025-35. doi: 10.1042/bj2881025. Biochem J. 1992. PMID: 1281979 Free PMC article.
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