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The influence of CYP2B6, CYP2C9 and CYP2D6 genotypes on the formation of the potent antioestrogen Z-4-hydroxy-tamoxifen in human liver.
Br J Clin Pharmacol. 2002 Aug;54(2):157-67. doi: 10.1046/j.1365-2125.2002.01614.x.
Br J Clin Pharmacol. 2002.
PMID: 12207635
Free PMC article.
Large interindividual variability in the in vitro formation of tamoxifen metabolites related to the development of genotoxicity.
Coller JK, Krebsfaenger N, Klein K, Wolbold R, Nüssler A, Neuhaus P, Zanger UM, Eichelbaum M, Mürdter TE.
Coller JK, et al. Among authors: krebsfaenger n.
Br J Clin Pharmacol. 2004 Jan;57(1):105-11. doi: 10.1046/j.1365-2125.2003.01970.x.
Br J Clin Pharmacol. 2004.
PMID: 14678348
Free PMC article.
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V79 Chinese hamster cells genetically engineered for polymorphic cytochrome P450 2D6 and their predictive value for humans.
Krebsfaenger N, Mürdter TE, Zanger UM, Eichelbaum MF, Doehmer J.
Krebsfaenger N, et al.
ALTEX. 2003;20(3):143-54.
ALTEX. 2003.
PMID: 12947487
Free article.
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Influence of CYP2D6 polymorphism on 3,4-methylenedioxymethamphetamine ('Ecstasy') cytotoxicity.
Carmo H, Brulport M, Hermes M, Oesch F, Silva R, Ferreira LM, Branco PS, Boer Dd, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG.
Carmo H, et al. Among authors: krebsfaenger n.
Pharmacogenet Genomics. 2006 Nov;16(11):789-99. doi: 10.1097/01.fpc.0000230419.05221.fc.
Pharmacogenet Genomics. 2006.
PMID: 17047487
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CYP2D6 increases toxicity of the designer drug 4-methylthioamphetamine (4-MTA).
Carmo H, Brulport M, Hermes M, Oesch F, de Boer D, Remião F, Carvalho F, Schön MR, Krebsfaenger N, Doehmer J, Bastos Mde L, Hengstler JG.
Carmo H, et al. Among authors: krebsfaenger n.
Toxicology. 2007 Jan 18;229(3):236-44. doi: 10.1016/j.tox.2006.10.024. Epub 2006 Dec 5.
Toxicology. 2007.
PMID: 17156908
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[Innovative cell culture methods in drug development].
Schleger C, Krebsfaenger N, Kalkuhl A, Bader R, Singer T.
Schleger C, et al. Among authors: krebsfaenger n.
ALTEX. 2001;18(1):5-8.
ALTEX. 2001.
PMID: 11248842
German.
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Relationship of cellular topoisomerase IIα inhibition to cytotoxicity and published genotoxicity of fluoroquinolone antibiotics in V79 cells.
Williams GM, Brunnemann KD, Smart DJ, Molina D, Jeffrey AM, Duan JD, Krebsfaenger N, Kampkoetter A, Schmuck G.
Williams GM, et al. Among authors: krebsfaenger n.
Chem Biol Interact. 2013 Apr 25;203(2):386-90. doi: 10.1016/j.cbi.2013.01.003. Epub 2013 Jan 20.
Chem Biol Interact. 2013.
PMID: 23340199
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