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229 results
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Immunotoxins in cancer therapy.
Kreitman RJ. Kreitman RJ. Curr Opin Immunol. 1999 Oct;11(5):570-8. doi: 10.1016/s0952-7915(99)00005-9. Curr Opin Immunol. 1999. PMID: 10508704 Review.
Targeting growth factor receptors with fusion toxins.
Kreitman RJ, FitzGerald D, Pastan I. Kreitman RJ, et al. Int J Immunopharmacol. 1992 Apr;14(3):465-72. doi: 10.1016/0192-0561(92)90177-m. Int J Immunopharmacol. 1992. PMID: 1319965 Review.
Mik-beta 1(Fv)-PE40, a recombinant immunotoxin cytotoxic toward cells bearing the beta-chain of the IL-2 receptor.
Kreitman RJ, Schneider WP, Queen C, Tsudo M, Fitzgerald DJ, Waldmann TA, Pastan I. Kreitman RJ, et al. J Immunol. 1992 Oct 15;149(8):2810-5. J Immunol. 1992. PMID: 1401913
Recombinant toxins containing the variable domains of the anti-Tac monoclonal antibody to the interleukin-2 receptor kill malignant cells from patients with chronic lymphocytic leukemia.
Kreitman RJ, Chaudhary VK, Kozak RW, FitzGerald DJ, Waldman TA, Pastan I. Kreitman RJ, et al. Blood. 1992 Nov 1;80(9):2344-52. Blood. 1992. PMID: 1421405
Interleukin-6 fused to a mutant form of Pseudomonas exotoxin kills malignant cells from patients with multiple myeloma.
Kreitman RJ, Siegall CB, FitzGerald DJ, Epstein J, Barlogie B, Pastan I. Kreitman RJ, et al. Blood. 1992 Apr 1;79(7):1775-80. Blood. 1992. PMID: 1558971
Rational design of a chimeric toxin: an intramolecular location for the insertion of transforming growth factor alpha within Pseudomonas exotoxin as a targeting ligand.
Kreitman RJ, Chaudhary VK, Siegall CB, FitzGerald DJ, Pastan I. Kreitman RJ, et al. Bioconjug Chem. 1992 Jan-Feb;3(1):58-62. doi: 10.1021/bc00013a009. Bioconjug Chem. 1992. PMID: 1616950
Properties of chimeric toxins with two recognition domains: interleukin 6 and transforming growth factor alpha at different locations in Pseudomonas exotoxin.
Kreitman RJ, Siegall CB, Chaudhary VK, FitzGerald DJ, Pastan I. Kreitman RJ, et al. Bioconjug Chem. 1992 Jan-Feb;3(1):63-8. doi: 10.1021/bc00013a010. Bioconjug Chem. 1992. PMID: 1616951
Generation of chimeric toxins.
FitzGerald D, Chaudhary VK, Kreitman RJ, Siegall CB, Pastan I. FitzGerald D, et al. Among authors: kreitman rj. Targeted Diagn Ther. 1992;7:447-62. Targeted Diagn Ther. 1992. PMID: 1633306 Review. No abstract available.
Antitumor effects of interleukin 6-Pseudomonas exotoxin chimeric molecules against the human hepatocellular carcinoma, PLC/PRF/5 in mice.
Siegall CB, Kreitman RJ, FitzGerald DJ, Pastan I. Siegall CB, et al. Among authors: kreitman rj. Cancer Res. 1991 Jun 1;51(11):2831-6. Cancer Res. 1991. PMID: 1851660
The recombinant immunotoxin anti-Tac(Fv)-Pseudomonas exotoxin 40 is cytotoxic toward peripheral blood malignant cells from patients with adult T-cell leukemia.
Kreitman RJ, Chaudhary VK, Waldmann T, Willingham MC, FitzGerald DJ, Pastan I. Kreitman RJ, et al. Proc Natl Acad Sci U S A. 1990 Nov;87(21):8291-5. doi: 10.1073/pnas.87.21.8291. Proc Natl Acad Sci U S A. 1990. PMID: 2236041 Free PMC article.
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