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Methylation status of HPV16 E2-binding sites classifies subtypes of HPV-associated oropharyngeal cancers.
Reuschenbach M, Huebbers CU, Prigge ES, Bermejo JL, Kalteis MS, Preuss SF, Seuthe IM, Kolligs J, Speel EJ, Olthof N, Kremer B, Wagner S, Klussmann JP, Vinokurova S, von Knebel Doeberitz M. Reuschenbach M, et al. Among authors: kremer b. Cancer. 2015 Jun 15;121(12):1966-76. doi: 10.1002/cncr.29315. Epub 2015 Mar 2. Cancer. 2015. PMID: 25731880 Free article.
P16(INK4A) immunostaining is a strong indicator for high-risk-HPV-associated oropharyngeal carcinomas and dysplasias, but is unreliable to predict low-risk-HPV-infection in head and neck papillomas and laryngeal dysplasias.
Mooren JJ, Gültekin SE, Straetmans JM, Haesevoets A, Peutz-Kootstra CJ, Huebbers CU, Dienes HP, Wieland U, Ramaekers FC, Kremer B, Speel EJ, Klussmann JP. Mooren JJ, et al. Among authors: kremer b. Int J Cancer. 2014 May 1;134(9):2108-17. doi: 10.1002/ijc.28534. Epub 2013 Oct 21. Int J Cancer. 2014. PMID: 24127203 Free article.
Comprehensive analysis of HPV16 integration in OSCC reveals no significant impact of physical status on viral oncogene and virally disrupted human gene expression.
Olthof NC, Speel EJ, Kolligs J, Haesevoets A, Henfling M, Ramaekers FC, Preuss SF, Drebber U, Wieland U, Silling S, Lam WL, Vucic EA, Kremer B, Klussmann JP, Huebbers CU. Olthof NC, et al. Among authors: kremer b. PLoS One. 2014 Feb 24;9(2):e88718. doi: 10.1371/journal.pone.0088718. eCollection 2014. PLoS One. 2014. PMID: 24586376 Free PMC article.
Viral load, gene expression and mapping of viral integration sites in HPV16-associated HNSCC cell lines.
Olthof NC, Huebbers CU, Kolligs J, Henfling M, Ramaekers FC, Cornet I, van Lent-Albrechts JA, Stegmann AP, Silling S, Wieland U, Carey TE, Walline HM, Gollin SM, Hoffmann TK, de Winter J, Kremer B, Klussmann JP, Speel EJ. Olthof NC, et al. Among authors: kremer b. Int J Cancer. 2015 Mar 1;136(5):E207-18. doi: 10.1002/ijc.29112. Epub 2014 Aug 14. Int J Cancer. 2015. PMID: 25082736 Free PMC article.
Upregulation of AKR1C1 and AKR1C3 expression in OPSCC with integrated HPV16 and HPV-negative tumors is an indicator of poor prognosis.
Huebbers CU, Verhees F, Poluschkin L, Olthof NC, Kolligs J, Siefer OG, Henfling M, Ramaekers FCS, Preuss SF, Beutner D, Seehawer J, Drebber U, Korkmaz Y, Lam WL, Vucic EA, Kremer B, Klussmann JP, Speel EM. Huebbers CU, et al. Among authors: kremer b. Int J Cancer. 2019 May 15;144(10):2465-2477. doi: 10.1002/ijc.31954. Epub 2019 Jan 30. Int J Cancer. 2019. PMID: 30367463 Free article.
Different prognostic models for different patient populations: validation of a new prognostic model for patients with oropharyngeal cancer in Western Europe.
Rietbergen MM, Witte BI, Velazquez ER, Snijders PJ, Bloemena E, Speel EJ, Brakenhoff RH, Kremer B, Lambin P, Leemans CR. Rietbergen MM, et al. Among authors: kremer b. Br J Cancer. 2015 May 26;112(11):1733-6. doi: 10.1038/bjc.2015.139. Epub 2015 May 7. Br J Cancer. 2015. PMID: 25950384 Free PMC article.
573 results