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Antitumor Effects of CAR T Cells Redirected to the EDB Splice Variant of Fibronectin.
Wagner J, Wickman E, Shaw TI, Anido AA, Langfitt D, Zhang J, Porter SN, Pruett-Miller SM, Tillman H, Krenciute G, Gottschalk S. Wagner J, et al. Among authors: krenciute g. Cancer Immunol Res. 2020 Dec 22. doi: 10.1158/2326-6066.CIR-20-0280. Online ahead of print. Cancer Immunol Res. 2020. PMID: 33355188
Cell surface antigen profiling of pediatric brain tumors: B7-H3 is consistently expressed and can be targeted via local or systemic CAR T-cell delivery.
Haydar D, Houke H, Chiang J, Yi Z, Odé Z, Caldwell K, Zhu X, Mercer KS, Stripay JL, Shaw TI, Vogel P, DeRenzo C, Baker SJ, Roussel MF, Gottschalk S, Krenciute G. Haydar D, et al. Among authors: krenciute g. Neuro Oncol. 2020 Dec 15:noaa278. doi: 10.1093/neuonc/noaa278. Online ahead of print. Neuro Oncol. 2020. PMID: 33320196
Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells.
Nguyen P, Okeke E, Clay M, Haydar D, Justice J, O'Reilly C, Pruett-Miller S, Papizan J, Moore J, Zhou S, Throm R, Krenciute G, Gottschalk S, DeRenzo C. Nguyen P, et al. Among authors: krenciute g. Mol Ther Oncolytics. 2020 Jun 23;18:202-214. doi: 10.1016/j.omto.2020.06.018. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728609 Free PMC article.
CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity.
Lazzarotto CR, Malinin NL, Li Y, Zhang R, Yang Y, Lee G, Cowley E, He Y, Lan X, Jividen K, Katta V, Kolmakova NG, Petersen CT, Qi Q, Strelcov E, Maragh S, Krenciute G, Ma J, Cheng Y, Tsai SQ. Lazzarotto CR, et al. Among authors: krenciute g. Nat Biotechnol. 2020 Nov;38(11):1317-1327. doi: 10.1038/s41587-020-0555-7. Epub 2020 Jun 15. Nat Biotechnol. 2020. PMID: 32541958 Free PMC article.
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