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DNA methylation analysis on purified neurons and glia dissects age and Alzheimer's disease-specific changes in the human cortex.
Gasparoni G, Bultmann S, Lutsik P, Kraus TFJ, Sordon S, Vlcek J, Dietinger V, Steinmaurer M, Haider M, Mulholland CB, Arzberger T, Roeber S, Riemenschneider M, Kretzschmar HA, Giese A, Leonhardt H, Walter J. Gasparoni G, et al. Among authors: kretzschmar ha. Epigenetics Chromatin. 2018 Jul 25;11(1):41. doi: 10.1186/s13072-018-0211-3. Epigenetics Chromatin. 2018. PMID: 30045751 Free PMC article.
Altered Long Noncoding RNA Expression Precedes the Course of Parkinson's Disease-a Preliminary Report.
Kraus TFJ, Haider M, Spanner J, Steinmaurer M, Dietinger V, Kretzschmar HA. Kraus TFJ, et al. Among authors: kretzschmar ha. Mol Neurobiol. 2017 May;54(4):2869-2877. doi: 10.1007/s12035-016-9854-x. Epub 2016 Mar 28. Mol Neurobiol. 2017. PMID: 27021022
Profiling of methylation and demethylation pathways during brain development and ageing.
Kraus TF, Kilinc S, Steinmaurer M, Stieglitz M, Guibourt V, Kretzschmar HA. Kraus TF, et al. Among authors: kretzschmar ha. J Neural Transm (Vienna). 2016 Mar;123(3):189-203. doi: 10.1007/s00702-015-1469-2. Epub 2015 Oct 26. J Neural Transm (Vienna). 2016. PMID: 26497022
Reducing tau aggregates with anle138b delays disease progression in a mouse model of tauopathies.
Wagner J, Krauss S, Shi S, Ryazanov S, Steffen J, Miklitz C, Leonov A, Kleinknecht A, Göricke B, Weishaupt JH, Weckbecker D, Reiner AM, Zinth W, Levin J, Ehninger D, Remy S, Kretzschmar HA, Griesinger C, Giese A, Fuhrmann M. Wagner J, et al. Among authors: kretzschmar ha. Acta Neuropathol. 2015 Nov;130(5):619-31. doi: 10.1007/s00401-015-1483-3. Epub 2015 Oct 6. Acta Neuropathol. 2015. PMID: 26439832 Free PMC article.
Three novel presenilin 1 mutations marking the wide spectrum of age at onset and clinical patterns in familial Alzheimer's disease.
Roeber S, Müller-Sarnowski F, Kress J, Edbauer D, Kuhlmann T, Tüttelmann F, Schindler C, Winter P, Arzberger T, Müller U, Danek A, Kretzschmar HA. Roeber S, et al. Among authors: kretzschmar ha. J Neural Transm (Vienna). 2015 Dec;122(12):1715-9. doi: 10.1007/s00702-015-1450-0. Epub 2015 Sep 8. J Neural Transm (Vienna). 2015. PMID: 26350633
Genetic Characterization of Ten-Eleven-Translocation Methylcytosine Dioxygenase Alterations in Human Glioma.
Kraus TF, Greiner A, Steinmaurer M, Dietinger V, Guibourt V, Kretzschmar HA. Kraus TF, et al. Among authors: kretzschmar ha. J Cancer. 2015 Jul 15;6(9):832-42. doi: 10.7150/jca.12010. eCollection 2015. J Cancer. 2015. PMID: 26284134 Free PMC article.
Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues.
Wagner M, Steinbacher J, Kraus TF, Michalakis S, Hackner B, Pfaffeneder T, Perera A, Müller M, Giese A, Kretzschmar HA, Carell T. Wagner M, et al. Among authors: kretzschmar ha. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12511-4. doi: 10.1002/anie.201502722. Epub 2015 Jul 3. Angew Chem Int Ed Engl. 2015. PMID: 26137924 Free PMC article.
Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy.
Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NCA, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, Farlow MR, Grafman J, Huey ED, Ryung Han M, Beecher S, Geller ET, Kretzschmar HA, Roeber S, Gearing M, Juncos JL, Vonsattel JPG, Van Deerlin VM, Grossman M, Hurtig HI, Gross RG, Arnold SE, Trojanowski JQ, Lee VM, Wenning GK, White CL, Höglinger GU, Müller U, Devlin B, Golbe LI, Crook J, Parisi JE, Boeve BF, Josephs KA, Wszolek ZK, Uitti RJ, Graff-Radford NR, Litvan I, Younkin SG, Wang LS, Ertekin-Taner N, Rademakers R, Hakonarsen H, Schellenberg GD, Dickson DW. Kouri N, et al. Among authors: kretzschmar ha. Nat Commun. 2015 Jun 16;6:7247. doi: 10.1038/ncomms8247. Nat Commun. 2015. PMID: 26077951 Free PMC article.
Clinical findings and diagnosis in genetic prion diseases in Germany.
Krasnianski A, Heinemann U, Ponto C, Kortt J, Kallenberg K, Varges D, Schulz-Schaeffer WJ, Kretzschmar HA, Zerr I. Krasnianski A, et al. Among authors: kretzschmar ha. Eur J Epidemiol. 2016 Feb;31(2):187-96. doi: 10.1007/s10654-015-0049-y. Epub 2015 Jun 16. Eur J Epidemiol. 2016. PMID: 26076917
Loss of 5-hydroxymethylcytosine and intratumoral heterogeneity as an epigenomic hallmark of glioblastoma.
Kraus TF, Kolck G, Greiner A, Schierl K, Guibourt V, Kretzschmar HA. Kraus TF, et al. Among authors: kretzschmar ha. Tumour Biol. 2015 Nov;36(11):8439-46. doi: 10.1007/s13277-015-3606-9. Epub 2015 May 29. Tumour Biol. 2015. PMID: 26022161
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