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Preclinical pharmacology of desloratadine, a selective and nonsedating histamine H1 receptor antagonist. 2nd communication: lack of central nervous system and cardiovascular effects.
Kreutner W, Hey JA, Chiu P, Barnett A. Kreutner W, et al. Arzneimittelforschung. 2000 May;50(5):441-8. doi: 10.1055/s-0031-1300228. Arzneimittelforschung. 2000. PMID: 10858871
Studies on the pharmacology of the novel histamine H3 receptor agonist Sch 50971.
Hey JA, Aslanian R, Bolser DC, Chapman RW, Egan RW, Rizzo CA, Shih NY, Fernandez X, McLeod RL, West R, Kreutner W. Hey JA, et al. Arzneimittelforschung. 1998 Sep;48(9):881-8. Arzneimittelforschung. 1998. PMID: 9793613
Effect of Sch 55700, a humanized monoclonal antibody to human interleukin-5, on eosinophilic responses and bronchial hyperreactivity.
Egan RW, Athwal D, Bodmer MW, Carter JM, Chapman RW, Chou CC, Cox MA, Emtage JS, Fernandez X, Genatt N, Indelicato SR, Jenh CH, Kreutner W, Kung TT, Mauser PJ, Minnicozzi M, Murgolo NJ, Narula SK, Petro ME, Schilling A, Sehring S, Stelts D, Stephens S, Taremi SS, Zurcher J, et al. Egan RW, et al. Arzneimittelforschung. 1999 Sep;49(9):779-90. doi: 10.1055/s-0031-1300502. Arzneimittelforschung. 1999. PMID: 10514907
Anti-inflammatory activity of inhaled mometasone furoate in allergic mice.
Chapman RW, Sehring SJ, Garlisi CG, Falcone A, Kung TT, Stelts D, Minnicozzi M, Jones H, Umland S, Egan RW, Kreutner W. Chapman RW, et al. Arzneimittelforschung. 1998 Apr;48(4):384-91. Arzneimittelforschung. 1998. PMID: 9608881
Effect of combined histamine H1 and H3 receptor blockade on cutaneous microvascular permeability elicited by compound 48/80.
McLeod RL, Mingo GG, Kreutner W, Hey JA. McLeod RL, et al. Among authors: kreutner w. Life Sci. 2005 Mar 4;76(16):1787-94. doi: 10.1016/j.lfs.2004.08.033. Epub 2005 Jan 22. Life Sci. 2005. PMID: 15698856
Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor.
Wu RL, Anthes JC, Kreutner W, Harris AG, West RE Jr. Wu RL, et al. Among authors: kreutner w. Int Arch Allergy Immunol. 2004 Dec;135(4):313-8. doi: 10.1159/000082325. Epub 2004 Nov 24. Int Arch Allergy Immunol. 2004. PMID: 15564772
SCH 206272: a potent, orally active tachykinin NK(1), NK(2), and NK(3) receptor antagonist.
Anthes JC, Chapman RW, Richard C, Eckel S, Corboz M, Hey JA, Fernandez X, Greenfeder S, McLeod R, Sehring S, Rizzo C, Crawley Y, Shih NY, Piwinski J, Reichard G, Ting P, Carruthers N, Cuss FM, Billah M, Kreutner W, Egan RW. Anthes JC, et al. Among authors: kreutner w. Eur J Pharmacol. 2002 Aug 23;450(2):191-202. doi: 10.1016/s0014-2999(02)02124-6. Eur J Pharmacol. 2002. PMID: 12206858
Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.
Billah MM, Cooper N, Minnicozzi M, Warneck J, Wang P, Hey JA, Kreutner W, Rizzo CA, Smith SR, Young S, Chapman RW, Dyke H, Shih NY, Piwinski JJ, Cuss FM, Montana J, Ganguly AK, Egan RW. Billah MM, et al. Among authors: kreutner w. J Pharmacol Exp Ther. 2002 Jul;302(1):127-37. doi: 10.1124/jpet.302.1.127. J Pharmacol Exp Ther. 2002. PMID: 12065709 Clinical Trial.
Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor.
Anthes JC, Gilchrest H, Richard C, Eckel S, Hesk D, West RE Jr, Williams SM, Greenfeder S, Billah M, Kreutner W, Egan RE. Anthes JC, et al. Among authors: kreutner w. Eur J Pharmacol. 2002 Aug 9;449(3):229-37. doi: 10.1016/s0014-2999(02)02049-6. Eur J Pharmacol. 2002. PMID: 12167464
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