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The triple uptake inhibitor (1R,5S)-(+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0] hexane hydrochloride (DOV 21947) reduces body weight and plasma triglycerides in rodent models of diet-induced obesity.
Tizzano JP, Stribling DS, Perez-Tilve D, Strack A, Frassetto A, Chen RZ, Fong TM, Shearman L, Krieter PA, Tschöp MH, Skolnick P, Basile AS. Tizzano JP, et al. Among authors: krieter pa. J Pharmacol Exp Ther. 2008 Mar;324(3):1111-26. doi: 10.1124/jpet.107.133132. Epub 2007 Dec 18. J Pharmacol Exp Ther. 2008. PMID: 18089843
Effects of the triple monoamine uptake inhibitor DOV 102,677 on alcohol-motivated responding and antidepressant activity in alcohol-preferring (P) rats.
Yang AR, Yi HS, Warnock KT, Mamczarz J, June HL Jr, Mallick N, Krieter PA, Tonelli L, Skolnick P, Basile AS, June HL Sr. Yang AR, et al. Among authors: krieter pa. Alcohol Clin Exp Res. 2012 May;36(5):863-73. doi: 10.1111/j.1530-0277.2011.01671.x. Epub 2011 Dec 7. Alcohol Clin Exp Res. 2012. PMID: 22150508 Free PMC article.
34 results